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Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1.
Panfili E, Rezzi SJ, Adamo A, Mazzoletti D, Massarotti A, Miggiano R, Fallarini S, Ambrosino S, Coletti A, Molinaro P, Milella M, Paiella S, Macchiarulo A, Ugel S, Pirali T, Pallotta MT. Panfili E, et al. Among authors: pallotta mt. ACS Pharmacol Transl Sci. 2024 Sep 12;7(10):3056-3070. doi: 10.1021/acsptsci.4c00265. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39421661
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity.
Serafini M, Torre E, Aprile S, Grosso ED, Gesù A, Griglio A, Colombo G, Travelli C, Paiella S, Adamo A, Orecchini E, Coletti A, Pallotta MT, Ugel S, Massarotti A, Pirali T, Fallarini S. Serafini M, et al. Among authors: pallotta mt. J Med Chem. 2020 Mar 26;63(6):3047-3065. doi: 10.1021/acs.jmedchem.9b01809. Epub 2020 Mar 17. J Med Chem. 2020. PMID: 32150677
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry.
Coletti A, Greco FA, Dolciami D, Camaioni E, Sardella R, Pallotta MT, Volpi C, Orabona C, Grohmann U, Macchiarulo A. Coletti A, et al. Among authors: pallotta mt. Medchemcomm. 2017 May 16;8(7):1378-1392. doi: 10.1039/c7md00109f. eCollection 2017 Jul 1. Medchemcomm. 2017. PMID: 30108849 Free PMC article. Review.
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Mondanelli G, Coletti A, Greco FA, Pallotta MT, Orabona C, Iacono A, Belladonna ML, Albini E, Panfili E, Fallarino F, Gargaro M, Manni G, Matino D, Carvalho A, Cunha C, Maciel P, Di Filippo M, Gaetani L, Bianchi R, Vacca C, Iamandii IM, Proietti E, Boscia F, Annunziato L, Peppelenbosch M, Puccetti P, Calabresi P, Macchiarulo A, Santambrogio L, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: pallotta mt. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3848-3857. doi: 10.1073/pnas.1918215117. Epub 2020 Feb 5. Proc Natl Acad Sci U S A. 2020. PMID: 32024760 Free PMC article.
Moonlighting Proteins Are Important Players in Cancer Immunology.
Adamo A, Frusteri C, Pallotta MT, Pirali T, Sartoris S, Ugel S. Adamo A, et al. Among authors: pallotta mt. Front Immunol. 2021 Jan 18;11:613069. doi: 10.3389/fimmu.2020.613069. eCollection 2020. Front Immunol. 2021. PMID: 33584695 Free PMC article. Review.
Membrane Localization and Phosphorylation of Indoleamine 2,3-Dioxygenase 2 (IDO2) in A549 Human Lung Adenocarcinoma Cells: First Steps in Exploring Its Signaling Function.
Suvieri C, De Marchis F, Mandarano M, Ambrosino S, Rossini S, Mondanelli G, Gargaro M, Panfili E, Orabona C, Pallotta MT, Belladonna ML, Volpi C. Suvieri C, et al. Among authors: pallotta mt. Int J Mol Sci. 2023 Nov 12;24(22):16236. doi: 10.3390/ijms242216236. Int J Mol Sci. 2023. PMID: 38003426 Free PMC article.
61 results