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MINCLE and TLR9 agonists synergize to induce Th1/Th17 vaccine memory and mucosal recall in mice and non-human primates.
Woodworth JS, Contreras V, Christensen D, Naninck T, Kahlaoui N, Gallouët AS, Langlois S, Burban E, Joly C, Gros W, Dereuddre-Bosquet N, Morin J, Liu Olsen M, Rosenkrands I, Stein AK, Krøyer Wood G, Follmann F, Lindenstrøm T, Hu T, Le Grand R, Pedersen GK, Mortensen R. Woodworth JS, et al. Among authors: christensen d. Nat Commun. 2024 Oct 17;15(1):8959. doi: 10.1038/s41467-024-52863-9. Nat Commun. 2024. PMID: 39420177 Free PMC article.
Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses.
Davidsen J, Rosenkrands I, Christensen D, Vangala A, Kirby D, Perrie Y, Agger EM, Andersen P. Davidsen J, et al. Among authors: christensen d. Biochim Biophys Acta. 2005 Dec 10;1718(1-2):22-31. doi: 10.1016/j.bbamem.2005.10.011. Epub 2005 Nov 14. Biochim Biophys Acta. 2005. PMID: 16321607 Free article.
Cationic liposomes as vaccine adjuvants.
Christensen D, Korsholm KS, Rosenkrands I, Lindenstrøm T, Andersen P, Agger EM. Christensen D, et al. Expert Rev Vaccines. 2007 Oct;6(5):785-96. doi: 10.1586/14760584.6.5.785. Expert Rev Vaccines. 2007. PMID: 17931158 Free article. Review.
Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements.
Agger EM, Rosenkrands I, Hansen J, Brahimi K, Vandahl BS, Aagaard C, Werninghaus K, Kirschning C, Lang R, Christensen D, Theisen M, Follmann F, Andersen P. Agger EM, et al. Among authors: christensen d. PLoS One. 2008 Sep 8;3(9):e3116. doi: 10.1371/journal.pone.0003116. PLoS One. 2008. PMID: 18776936 Free PMC article.
Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin.
Andersen CA, Rosenkrands I, Olsen AW, Nordly P, Christensen D, Lang R, Kirschning C, Gomes JM, Bhowruth V, Minnikin DE, Besra GS, Follmann F, Andersen P, Agger EM. Andersen CA, et al. Among authors: christensen d. J Immunol. 2009 Aug 15;183(4):2294-302. doi: 10.4049/jimmunol.0804091. Epub 2009 Jul 20. J Immunol. 2009. PMID: 19620310
Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response.
Henriksen-Lacey M, Christensen D, Bramwell VW, Lindenstrøm T, Agger EM, Andersen P, Perrie Y. Henriksen-Lacey M, et al. Among authors: christensen d. J Control Release. 2010 Jul 14;145(2):102-8. doi: 10.1016/j.jconrel.2010.03.027. Epub 2010 Apr 8. J Control Release. 2010. PMID: 20381556
1,182 results