Tatum NJ - Search Results

1

Structural requirements for the specific binding of CRABP2 to cyclin D3.

Pastok MW, Tomlinson CWE, Turberville S, Butler AM, Baslé A, Noble MEM, Endicott JA, Pohl E, Tatum NJ. Pastok MW, et al. Among authors: tatum nj. Structure. 2024 Dec 5;32(12):2301-2315.e6. doi: 10.1016/j.str.2024.09.020. Epub 2024 Oct 16. Structure. 2024. PMID: 39419021 Free article.

2

Structural and docking studies of potent ethionamide boosters.

Tatum NJ, Villemagne B, Willand N, Deprez B, Liebeschuetz JW, Baulard AR, Pohl E. Tatum NJ, et al. Acta Crystallogr C. 2013 Nov;69(Pt 11):1243-50. doi: 10.1107/S0108270113028126. Epub 2013 Oct 24. Acta Crystallogr C. 2013. PMID: 24192167

3

New active leads for tuberculosis booster drugs by structure-based drug discovery.

Tatum NJ, Liebeschuetz JW, Cole JC, Frita R, Herledan A, Baulard AR, Willand N, Pohl E. Tatum NJ, et al. Org Biomol Chem. 2017 Dec 13;15(48):10245-10255. doi: 10.1039/c7ob00910k. Org Biomol Chem. 2017. PMID: 29182187

4

Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids.

Haffez H, Chisholm DR, Tatum NJ, Valentine R, Redfern C, Pohl E, Whiting A, Przyborski S. Haffez H, et al. Among authors: tatum nj. Bioorg Med Chem. 2018 May 1;26(8):1560-1572. doi: 10.1016/j.bmc.2018.02.002. Epub 2018 Feb 10. Bioorg Med Chem. 2018. PMID: 29439915 Free PMC article.

5

Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.

Wood DJ, Korolchuk S, Tatum NJ, Wang LZ, Endicott JA, Noble MEM, Martin MP. Wood DJ, et al. Among authors: tatum nj. Cell Chem Biol. 2019 Jan 17;26(1):121-130.e5. doi: 10.1016/j.chembiol.2018.10.015. Epub 2018 Nov 21. Cell Chem Biol. 2019. PMID: 30472117 Free PMC article.

6

Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds.

Tatum NJ, Duarte F, Kamerlin SCL, Pohl E. Tatum NJ, et al. J Phys Chem Lett. 2019 May 2;10(9):2244-2249. doi: 10.1021/acs.jpclett.9b00741. Epub 2019 Apr 23. J Phys Chem Lett. 2019. PMID: 30965004 Free PMC article.

7

Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors.

Lochhead PA, Tucker JA, Tatum NJ, Wang J, Oxley D, Kidger AM, Johnson VP, Cassidy MA, Gray NS, Noble MEM, Cook SJ. Lochhead PA, et al. Among authors: tatum nj. Nat Commun. 2020 Mar 13;11(1):1383. doi: 10.1038/s41467-020-15031-3. Nat Commun. 2020. PMID: 32170057 Free PMC article.

8

Chatterboxes: the structural and functional diversity of cyclins.

Tatum NJ, Endicott JA. Tatum NJ, et al. Semin Cell Dev Biol. 2020 Nov;107:4-20. doi: 10.1016/j.semcdb.2020.04.021. Epub 2020 May 13. Semin Cell Dev Biol. 2020. PMID: 32414682 Review.

9

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation.

Salamina M, Montefiore BC, Liu M, Wood DJ, Heath R, Ault JR, Wang LZ, Korolchuk S, Baslé A, Pastok MW, Reeks J, Tatum NJ, Sobott F, Arold ST, Pagano M, Noble MEM, Endicott JA. Salamina M, et al. Among authors: tatum nj. J Mol Biol. 2021 Mar 5;433(5):166795. doi: 10.1016/j.jmb.2020.166795. Epub 2021 Jan 7. J Mol Biol. 2021. PMID: 33422522 Free PMC article.

10

Crystallographic fragment screening in academic cancer drug discovery.

Martin MP, Endicott JA, Noble MEM, Tatum NJ. Martin MP, et al. Among authors: tatum nj. Methods Enzymol. 2023;690:211-234. doi: 10.1016/bs.mie.2023.06.021. Epub 2023 Jul 11. Methods Enzymol. 2023. PMID: 37858530

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