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Page 1
Novel Corrector for Variants of SLC6A8: A Therapeutic Opportunity for Creatine Transporter Deficiency.
Gechijian LN, Muncipinto G, Rettenmaier TJ, Labenski MT, Rusu V, Rosskamp L, Conway L, van Kalken D, Gross L, Iantosca G, Crotty W, Mathis R, Park H, Rabin B, Westgate C, Lyons M, Deshusses C, Brandon N, Brown DG, Blanchette HS, Pullen N, Jones LH, Barrish JC. Gechijian LN, et al. Among authors: muncipinto g. ACS Chem Biol. 2024 Nov 15;19(11):2372-2382. doi: 10.1021/acschembio.4c00571. Epub 2024 Oct 17. ACS Chem Biol. 2024. PMID: 39418577 Free PMC article.
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine.
Wobst HJ, Viader A, Muncipinto G, Hollibaugh R, van Kalken D, Burkhart CT, Cantin SM, Bates RM, Regimbald-Dumas Y, Gross L, Antalek MT, Zweig JE, Wu F, Rettenmaier TJ, Labenski MT, Pullen N, Blanchette HS, Henderson JL, Weng HH, Vaughn TA, Brown DG, Throup JP, Barrish JC. Wobst HJ, et al. Among authors: muncipinto g. JCI Insight. 2024 Nov 8;9(21):e182876. doi: 10.1172/jci.insight.182876. JCI Insight. 2024. PMID: 39513367 Free PMC article. Clinical Trial.
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules.
Pisani L, Catto M, Muncipinto G, Nicolotti O, Carrieri A, Rullo M, Stefanachi A, Leonetti F, Altomare C. Pisani L, et al. Among authors: muncipinto g. Front Chem. 2022 Oct 10;10:1002547. doi: 10.3389/fchem.2022.1002547. eCollection 2022. Front Chem. 2022. PMID: 36300022 Free PMC article. Review.
Labeling Preferences of Diazirines with Protein Biomolecules.
West AV, Muncipinto G, Wu HY, Huang AC, Labenski MT, Jones LH, Woo CM. West AV, et al. Among authors: muncipinto g. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20. J Am Chem Soc. 2021. PMID: 33876925 Free PMC article.
Erratum: Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MWD, Duvall JR, Kihlberg J. Over B, et al. Among authors: muncipinto g. Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922a. Nat Chem Biol. 2017. PMID: 28853740 No abstract available.
Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile.
Duvall JR, Bedard L, Naylor-Olsen AM, Manson AL, Bittker JA, Sun W, Fitzgerald ME, He Z, Lee MD 4th, Marie JC, Muncipinto G, Rush D, Xu D, Xu H, Zhang M, Earl AM, Palmer MA, Foley MA, Vacca JP, Scherer CA. Duvall JR, et al. Among authors: muncipinto g. ACS Infect Dis. 2017 May 12;3(5):349-359. doi: 10.1021/acsinfecdis.6b00206. Epub 2017 Mar 7. ACS Infect Dis. 2017. PMID: 28215073 Free PMC article.
Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MW, Duvall JR, Kihlberg J. Over B, et al. Among authors: muncipinto g. Nat Chem Biol. 2016 Dec;12(12):1065-1074. doi: 10.1038/nchembio.2203. Epub 2016 Oct 17. Nat Chem Biol. 2016. PMID: 27748751
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.
Farina R, Pisani L, Catto M, Nicolotti O, Gadaleta D, Denora N, Soto-Otero R, Mendez-Alvarez E, Passos CS, Muncipinto G, Altomare CD, Nurisso A, Carrupt PA, Carotti A. Farina R, et al. Among authors: muncipinto g. J Med Chem. 2015 Jul 23;58(14):5561-78. doi: 10.1021/acs.jmedchem.5b00599. Epub 2015 Jul 9. J Med Chem. 2015. PMID: 26107513
Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.
Nagiec MM, Skepner AP, Negri J, Eichhorn M, Kuperwasser N, Comer E, Muncipinto G, Subramanian A, Clish C, Musunuru K, Duvall JR, Foley M, Perez JR, Palmer MA. Nagiec MM, et al. Among authors: muncipinto g. PLoS One. 2015 Mar 26;10(3):e0120295. doi: 10.1371/journal.pone.0120295. eCollection 2015. PLoS One. 2015. PMID: 25811180 Free PMC article.
20 results