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Lineage-specific CDK activity dynamics characterize early mammalian development.
Saykali B, Tran AD, Cornwell JA, Caldwell MA, Sangsari PR, Morgan NY, Kruhlak MJ, Cappell SD, Ruiz S. Saykali B, et al. Among authors: kruhlak mj. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.599098. doi: 10.1101/2024.06.14.599098. bioRxiv. 2024. PMID: 39372752 Free PMC article. Preprint.
Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4.
Mizunuma M, Redon CE, Saha LK, Tran AD, Dhall A, Sebastian R, Taniyama D, Kruhlak MJ, Reinhold WC, Takebe N, Pommier Y. Mizunuma M, et al. Among authors: kruhlak mj. Cancer Res Commun. 2024 Aug 1;4(8):2101-2111. doi: 10.1158/2767-9764.CRC-24-0093. Cancer Res Commun. 2024. PMID: 39041239 Free PMC article.
AGO2 silences mobile transposons in the nucleus of quiescent cells.
Sala L, Kumar M, Prajapat M, Chandrasekhar S, Cosby RL, La Rocca G, Macfarlan TS, Awasthi P, Chari R, Kruhlak M, Vidigal JA. Sala L, et al. Among authors: kruhlak m. Nat Struct Mol Biol. 2023 Dec;30(12):1985-1995. doi: 10.1038/s41594-023-01151-z. Epub 2023 Nov 20. Nat Struct Mol Biol. 2023. PMID: 37985687
Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR.
Zong D, Koussa NC, Cornwell JA, Pankajam AV, Kruhlak MJ, Wong N, Chari R, Cappell SD, Nussenzweig A. Zong D, et al. Among authors: kruhlak mj. bioRxiv [Preprint]. 2023 Jul 30:2023.07.28.550976. doi: 10.1101/2023.07.28.550976. bioRxiv. 2023. Update in: Genes Dev. 2023 Oct 1;37(19-20):913-928. doi: 10.1101/gad.351085.123. PMID: 37662356 Free PMC article. Updated. Preprint.
EWSR1's visual modalities are defined by its association with nucleic acids and RNA polymerase II.
Rajan SS, Ebegboni VJ, Pichling P, Ludwig KR, Jones TL, Chari R, Tran A, Kruhlak MJ, Loncarek J, Caplen NJ. Rajan SS, et al. Among authors: kruhlak mj. bioRxiv [Preprint]. 2023 Aug 16:2023.08.16.553246. doi: 10.1101/2023.08.16.553246. bioRxiv. 2023. Update in: Mol Cell Biol. 2024;44(3):103-122. doi: 10.1080/10985549.2024.2315425. PMID: 37645932 Free PMC article. Updated. Preprint.
121 results