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A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer.
Scales TQ, Smith B, Blanchard LM, Wixom N, Tuttle ET, Altman BJ, Peppone LJ, Munger J, Campbell TM, Campbell EK, Harris IS. Scales TQ, et al. medRxiv [Preprint]. 2024 Oct 22:2024.10.09.24315165. doi: 10.1101/2024.10.09.24315165. medRxiv. 2024. Update in: Cancer Metab. 2024 Dec 19;12(1):38. doi: 10.1186/s40170-024-00368-w PMID: 39417128 Free PMC article. Updated. Preprint.
Glutathione supports lipid abundance in vivo.
Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Duncan R, Rodriguez K, Hecht F, Zocchi M, Smorodintsev-Schiller L, Scales TQ, Taylor K, Alimohammadi F, Sechrist ZR, Agostini-Vulaj D, Schafer XL, Chang H, Smith Z, O'Connor TN, Whelan S, Selfors LM, Crowdis J, Gray GK, Bronson RT, Brenner D, Rufini A, Dirksen RT, Hezel AF, Huber AR, Munger J, Cravatt BF, Vasiliou V, Cole CL, DeNicola GM, Harris IS. Asantewaa G, et al. Among authors: scales tq. bioRxiv [Preprint]. 2023 Feb 11:2023.02.10.524960. doi: 10.1101/2023.02.10.524960. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 21;15(1):6152. doi: 10.1038/s41467-024-50454-2 PMID: 36798186 Free PMC article. Updated. Preprint.
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression.
Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Rodriguez K, Hecht F, Zocchi M, Smorodintsev-Schiller L, Scales TQ, Taylor K, Alimohammadi F, Duncan RP, Sechrist ZR, Agostini-Vulaj D, Schafer XL, Chang H, Smith ZR, O'Connor TN, Whelan S, Selfors LM, Crowdis J, Gray GK, Bronson RT, Brenner D, Rufini A, Dirksen RT, Hezel AF, Huber AR, Munger J, Cravatt BF, Vasiliou V, Cole CL, DeNicola GM, Harris IS. Asantewaa G, et al. Among authors: scales tq. Nat Commun. 2024 Jul 21;15(1):6152. doi: 10.1038/s41467-024-50454-2. Nat Commun. 2024. PMID: 39034312 Free PMC article.