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Page 1
Identification of targetable epigenetic vulnerabilities in uveal melanoma.
Yenisehirli G, Borges S, Braun SS, Zuniga AN, Quintana GI, Kutsnetsoff JN, Rodriguez S, Adis EV, Lopez S, Dollar JJ, Stathias V, Volmar CH, Karaca E, Brothers S, Bilbao D, Harbour JW, Correa ZM, Kurtenbach S. Yenisehirli G, et al. Among authors: bilbao d. bioRxiv [Preprint]. 2024 Oct 11:2024.10.11.617464. doi: 10.1101/2024.10.11.617464. bioRxiv. 2024. PMID: 39416076 Free PMC article. Preprint.
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Brabson JP, et al. Among authors: bilbao d. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. Cell Rep. 2023. PMID: 36848231 Free PMC article.
Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Zha M, Garcia-Martinez L, Bañuelos CP, Stransky S, Liu T, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar Benitah S, Cimmino L, Bilbao D, Sidoli S, Wang Z, Verdun RE, Morey L. Caeiro LD, et al. Among authors: bilbao d. Genes Dev. 2024 Feb 13;38(1-2):46-69. doi: 10.1101/gad.351408.123. Genes Dev. 2024. PMID: 38286657 Free PMC article.
Endocrine resistance and breast cancer plasticity are controlled by CoREST.
Garcia-Martinez L, Adams AM, Chan HL, Nakata Y, Weich N, Stransky S, Zhang Z, Alshalalfa M, Sarria L, Mahal BA, Kesmodel SB, Celià-Terrassa T, Liu Z, Minucci S, Bilbao D, Sidoli S, Verdun RE, Morey L. Garcia-Martinez L, et al. Among authors: bilbao d. Nat Struct Mol Biol. 2022 Nov;29(11):1122-1135. doi: 10.1038/s41594-022-00856-x. Epub 2022 Nov 7. Nat Struct Mol Biol. 2022. PMID: 36344844 Free PMC article.
Smoking induces WEE1 expression to promote docetaxel resistance in esophageal adenocarcinoma.
Islam MO, Thangaretnam K, Lu H, Peng D, Soutto M, El-Rifai W, Giordano S, Ban Y, Chen X, Bilbao D, Villarino AV, Schürer S, Hosein PJ, Chen Z. Islam MO, et al. Among authors: bilbao d. Mol Ther Oncolytics. 2023 Aug 28;30:286-300. doi: 10.1016/j.omto.2023.08.012. eCollection 2023 Sep 21. Mol Ther Oncolytics. 2023. PMID: 37732296 Free PMC article.
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression.
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl D, Beckedorff F, Tamiro F, Chen C, Duffort S, Itonaga H, Mookhtiar AK, Kunkalla K, Valencia AM, Collings CK, Kadoch C, Vega F, Kogan SC, Shiekhattar R, Morey L, Bilbao D, Nimer SD. Mas G, et al. Among authors: bilbao d. J Clin Invest. 2023 Jul 3;133(13):e158419. doi: 10.1172/JCI158419. J Clin Invest. 2023. PMID: 37200093 Free PMC article.
Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Garcia-Martinez L, Bañuelos CP, Stransky S, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar-Benitah S, Cimmino L, Bilbao D, Sidoli S, Verdun RE, Morey L. Caeiro LD, et al. Among authors: bilbao d. bioRxiv [Preprint]. 2023 Nov 6:2023.11.06.565847. doi: 10.1101/2023.11.06.565847. bioRxiv. 2023. Update in: Genes Dev. 2024 Feb 13;38(1-2):46-69. doi: 10.1101/gad.351408.123 PMID: 38076924 Free PMC article. Updated. Preprint.
Modeling Lymphoma Angiogenesis, Lymphangiogenesis, and Vessel Co-Option, and the Effects of Inhibition of Lymphoma-Vessel Interactions with an αCD20-EndoP125A Antibody Fusion Protein.
Elledge C, Zhang Y, Shin SU, Cho HM, Ramakrishnan S, Sankar A, Chapman JR, Bilbao D, Das R, Gil-Henn H, Lossos IS, Rosenblatt JD. Elledge C, et al. Among authors: bilbao d. Cells. 2024 Nov 6;13(22):1835. doi: 10.3390/cells13221835. Cells. 2024. PMID: 39594584 Free PMC article.
The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma.
Lightfuss OB, Kumar P, Li L, Shastri T, Newsam AD, Manara P, Alaoui AY, Parets DEH, Younes PA, Chahar D, Arumov A, Coughlin CA, Williams IP, Fattakhov N, Martinez AB, Landgren O, Schurer SC, Lemmon V, Maura F, Bilbao D, Feng Y, Al-Ali H, Schatz JH. Lightfuss OB, et al. Among authors: bilbao d. bioRxiv [Preprint]. 2024 Oct 26:2024.10.21.619489. doi: 10.1101/2024.10.21.619489. bioRxiv. 2024. PMID: 39484514 Free PMC article. Preprint.
55 results