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DNA lesions that block transcription induce the death of Trypanosoma cruzi via ATR activation, which is dependent on the presence of R-loops.
Mendes IC, Dos Reis Bertoldo W, Miranda-Junior AS, Assis AV, Repolês BM, Ferreira WRR, Chame DF, Souza DL, Pavani RS, Macedo AM, Franco GR, Serra E, Perdomo V, Menck CFM, da Silva Leandro G, Fragoso SP, Barbosa Elias MCQ, Machado CR. Mendes IC, et al. Among authors: serra e. DNA Repair (Amst). 2024 Sep;141:103726. doi: 10.1016/j.dnarep.2024.103726. Epub 2024 Jul 27. DNA Repair (Amst). 2024. PMID: 39096697
Triple Combination of MEK, BET, and CDK Inhibitors Significantly Reduces Human Malignant Peripheral Nerve Sheath Tumors in Mouse Models.
Ortega-Bertran S, Fernández-Rodríguez J, Magallón-Lorenz M, Zhang X, Creus-Bachiller E, Diazgranados AP, Uriarte-Arrazola I, Mazuelas H, Blanco I, Valverde C, Carrió M, Villanueva A, De Raedt T, Romagosa C, Gel B, Salvador H, Ferrer M, Lázaro C, Serra E. Ortega-Bertran S, et al. Among authors: serra e. Clin Cancer Res. 2024 Dec 30. doi: 10.1158/1078-0432.CCR-24-2807. Online ahead of print. Clin Cancer Res. 2024. PMID: 39786423
International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study.
Caron AGM, van Huizen AM, Musters AAH, Gerbens LAA, Middelkamp Hup MA, Flohr C, Irvine AD, Vestergaard C, Peris K, Brandling-Bennett HA, Drucker AM, Spuls PI; MTX Consensus for AD Survey Study Group. Caron AGM, et al. J Eur Acad Dermatol Venereol. 2024 Aug 1. doi: 10.1111/jdv.20271. Online ahead of print. J Eur Acad Dermatol Venereol. 2024. PMID: 39087636
Identification of novel bromodomain inhibitors of Trypanosoma cruzi bromodomain factor 2 (TcBDF2) using a fluorescence polarization-based high-throughput assay.
Tavernelli LE, Alonso VL, Peña I, Rodríguez Araya E, Manarin R, Cantizani J, Martin J, Salamanca J, Bamborough P, Calderón F, Gabarro R, Serra E. Tavernelli LE, et al. Among authors: serra e. Antimicrob Agents Chemother. 2024 Aug 7;68(8):e0024324. doi: 10.1128/aac.00243-24. Epub 2024 Jul 19. Antimicrob Agents Chemother. 2024. PMID: 39028190 Free PMC article.
Outcomes of Endoscopic Endonasal Dacryocystorhinostomy in Glaucoma Patients.
Pace GM, Giombi F, Muci G, Giunta G, Pirola F, Serra E, Zuppardo J, Ferreli F, Vinciguerra P, Mercante G, Maria AD, Spriano G, Malvezzi L. Pace GM, et al. Among authors: serra e. J Pers Med. 2024 Mar 27;14(4):348. doi: 10.3390/jpm14040348. J Pers Med. 2024. PMID: 38672975 Free PMC article.
435 results