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Amplified centrosomes-more than just a threat.
Kiermaier E, Stötzel I, Schapfl MA, Villunger A. Kiermaier E, et al. Among authors: schapfl ma. EMBO Rep. 2024 Oct;25(10):4153-4167. doi: 10.1038/s44319-024-00260-0. Epub 2024 Sep 16. EMBO Rep. 2024. PMID: 39285247 Free PMC article. Review.
Extra centrosomes delay DNA damage-driven tumorigenesis.
Braun VZ, Karbon G, Schuler F, Schapfl MA, Weiss JG, Petermann PY, Spierings DCJ, Tijhuis AE, Foijer F, Labi V, Villunger A. Braun VZ, et al. Among authors: schapfl ma. Sci Adv. 2024 Mar 29;10(13):eadk0564. doi: 10.1126/sciadv.adk0564. Epub 2024 Mar 29. Sci Adv. 2024. PMID: 38552015 Free PMC article.
The SKP2-p27 axis defines susceptibility to cell death upon CHK1 inhibition.
Lohmüller M, Roeck BF, Szabo TG, Schapfl MA, Pegka F, Herzog S, Villunger A, Schuler F. Lohmüller M, et al. Among authors: schapfl ma. Mol Oncol. 2022 Aug;16(15):2771-2787. doi: 10.1002/1878-0261.13264. Epub 2022 Jul 7. Mol Oncol. 2022. PMID: 35673965 Free PMC article.