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Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes.
O'Neill K, Pleasance E, Fan J, Akbari V, Chang G, Dixon K, Csizmok V, MacLennan S, Porter V, Galbraith A, Grisdale CJ, Culibrk L, Dupuis JH, Corbett R, Hopkins J, Bowlby R, Pandoh P, Smailus DE, Cheng D, Wong T, Frey C, Shen Y, Lewis E, Paulin LF, Sedlazeck FJ, Nelson JMT, Chuah E, Mungall KL, Moore RA, Coope R, Mungall AJ, McConechy MK, Williamson LM, Schrader KA, Yip S, Marra MA, Laskin J, Jones SJM. O'Neill K, et al. Among authors: dupuis jh. Cell Genom. 2024 Nov 13;4(11):100674. doi: 10.1016/j.xgen.2024.100674. Epub 2024 Oct 14. Cell Genom. 2024. PMID: 39406235 Free PMC article.
Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells.
Beetch M, Boycott C, Harandi-Zadeh S, Yang T, Martin BJE, Dixon-McDougall T, Ren K, Gacad A, Dupuis JH, Ullmer M, Lubecka K, Yada RY, Brown CJ, Howe LJ, Stefanska B. Beetch M, et al. Among authors: dupuis jh. J Nutr Biochem. 2021 Dec;98:108815. doi: 10.1016/j.jnutbio.2021.108815. Epub 2021 Jul 7. J Nutr Biochem. 2021. PMID: 34242723 Free PMC article.
Roles of Plant-Specific Inserts in Plant Defense.
Cheung LKY, Dupuis JH, Dee DR, Bryksa BC, Yada RY. Cheung LKY, et al. Among authors: dupuis jh. Trends Plant Sci. 2020 Jul;25(7):682-694. doi: 10.1016/j.tplants.2020.02.009. Epub 2020 Mar 19. Trends Plant Sci. 2020. PMID: 32526173 Review.
Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme.
Kesari P, Deshmukh A, Pahelkar N, Suryawanshi AB, Rathore I, Mishra V, Dupuis JH, Xiao H, Gustchina A, Abendroth J, Labaied M, Yada RY, Wlodawer A, Edwards TE, Lorimer DD, Bhaumik P. Kesari P, et al. Among authors: dupuis jh. Protein Sci. 2022 Apr;31(4):882-899. doi: 10.1002/pro.4279. Epub 2022 Feb 5. Protein Sci. 2022. PMID: 35048450 Free PMC article.
17 results