Chai SC - Search Results

1

Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2.

Scott DC, Dharuman S, Griffith E, Chai SC, Ronnebaum J, King MT, Tangallapally R, Lee C, Gee CT, Yang L, Li Y, Loudon VC, Lee HW, Ochoada J, Miller DJ, Jayasinghe T, Paulo JA, Elledge SJ, Harper JW, Chen T, Lee RE, Schulman BA. Scott DC, et al. Among authors: chai sc. Nat Commun. 2024 Oct 12;15(1):8829. doi: 10.1038/s41467-024-52966-3. Nat Commun. 2024. PMID: 39396041 Free article.

2

Circulating Plasma Proteins in Aortic Stenosis: Associations With Severity, Myocardial Response, and Clinical Outcomes.

Tan ESJ, Choi H, DeFilippi CR, Oon YY, Chan SP, Gong L, Lunaria JB, Liew OW, Chong JP, Tay EL, Soo WM, Yip JW, Yong QW, Lee EM, Daniel Yeo PS, Ding ZP, Tang HC, Ewe SH, Chin CWL, Chai SC, Goh PP, Ling LF, Ong HY, Richards AM, Ling LH. Tan ESJ, et al. Among authors: chai sc. J Am Heart Assoc. 2024 Oct;13(19):e035486. doi: 10.1161/JAHA.124.035486. Epub 2024 Sep 30. J Am Heart Assoc. 2024. PMID: 39344657 Free article.

3

Relative motion splints versus metacarpophalangeal joint blocking splints in the management of trigger finger: Study protocol for a randomized comparative trial.

Leong LX, Chai SC, Howell JW, Mohd Rasdi HF, Abdul Rahman NR. Leong LX, et al. Among authors: chai sc. PLoS One. 2024 Aug 13;19(8):e0307033. doi: 10.1371/journal.pone.0307033. eCollection 2024. PLoS One. 2024. PMID: 39137205 Free PMC article. Clinical Trial.

4

Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.

Garcia-Maldonado E, Huber AD, Chai SC, Nithianantham S, Li Y, Wu J, Poudel S, Miller DJ, Seetharaman J, Chen T. Garcia-Maldonado E, et al. Among authors: chai sc. Nat Commun. 2024 May 14;15(1):4054. doi: 10.1038/s41467-024-48472-1. Nat Commun. 2024. PMID: 38744881 Free PMC article.

5

The effectiveness of therapeutic craft-making activities in treating lower-third forearm fracture: study protocol for a randomized controlled trial.

Teoh RF, Chai SC, Razaob Razab NA, Amin MIM, Howell JW. Teoh RF, et al. Among authors: chai sc. Trials. 2024 Mar 12;25(1):184. doi: 10.1186/s13063-024-08008-w. Trials. 2024. PMID: 38475790 Free PMC article.

6

Oral-diadochokinesis between Parkinson's disease and neurotypical elderly among Malaysian-Malay speakers.

Ong YQ, Lee J, Chu SY, Chai SC, Gan KB, Ibrahim NM, Barlow SM. Ong YQ, et al. Among authors: chai sc. Int J Lang Commun Disord. 2024 Mar 7. doi: 10.1111/1460-6984.13025. Online ahead of print. Int J Lang Commun Disord. 2024. PMID: 38451114

7

A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR.

Huber AD, Poudel S, Wu J, Miller DJ, Lin W, Yang L, Bwayi MN, Rimmer MA, Gee RRF, Seetharaman J, Chai SC, Chen T. Huber AD, et al. Among authors: chai sc. Nucleic Acids Res. 2024 Feb 28;52(4):1661-1676. doi: 10.1093/nar/gkad1175. Nucleic Acids Res. 2024. PMID: 38084912 Free PMC article.

8

The standardised Malay version of purdue pegboard test: Content validity and test-retest reliability testing.

Poo YS, Chai SC, Goh PI, Kadar M, Razaob Razab NA. Poo YS, et al. Among authors: chai sc. Hong Kong J Occup Ther. 2023 Dec;36(2):84-91. doi: 10.1177/15691861231179012. Epub 2023 May 30. Hong Kong J Occup Ther. 2023. PMID: 38027054 Free PMC article.

9

Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors.

Buchholz CR, Sneddon MS, McPherson JE, Das S, Gee CT, Grillo MJ, Chai SC, Lee RE, Chen T, Harki DA, Shelat AA, Pomerantz WCK. Buchholz CR, et al. Among authors: chai sc. ACS Med Chem Lett. 2023 Oct 3;14(10):1441-1447. doi: 10.1021/acsmedchemlett.3c00343. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849548 Free PMC article.

10

Personalized lifetime prediction of survival and treatment benefit in patients with heart failure with reduced ejection fraction: The LIFE-HF model.

Burger PM, Savarese G, Tromp J, Adamson C, Jhund PS, Benson L, Hage C, Tay WT, Solomon SD, Packer M, Rossello X, McEvoy JW, De Bacquer D, Timmis A, Vardas P, Graham IM, Di Angelantonio E, Visseren FLJ, McMurray JJV, Lam CSP, Lund LH, Koudstaal S, Dorresteijn JAN, Mosterd A; European Society of Cardiology's Cardiovascular Risk Collaboration (ESC CRC). Burger PM, et al. Eur J Heart Fail. 2023 Nov;25(11):1962-1975. doi: 10.1002/ejhf.3028. Epub 2023 Sep 18. Eur J Heart Fail. 2023. PMID: 37691140

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