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Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research.
Chang MH, Barbar-Smiley F, Akoghlanian S, Drew J, Angeles-Han ST, Quinlan-Waters M, Bohnsack JF, Cooper AM, Edelheit B, Twachtman-Bassett J, Lerman MA, Nanda K, Rabinovich CE, Lo MS; CARRA Uveitis Workgroup and the CARRA Registry Investigators. Chang MH, et al. Pediatr Rheumatol Online J. 2024 Oct 7;22(1):88. doi: 10.1186/s12969-024-01022-x. Pediatr Rheumatol Online J. 2024. PMID: 39375683 Free PMC article.
Borrelia burgdorferi BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins.
Murphy BT, Wiepen JJ, Graham DE, Swanson SK, Kashipathy MM, Cooper A, Battaile KP, Johnson DK, Florens L, Blevins JS, Lovell S, Zückert WR. Murphy BT, et al. Among authors: lovell s. bioRxiv [Preprint]. 2024 Aug 6:2024.08.06.606844. doi: 10.1101/2024.08.06.606844. bioRxiv. 2024. PMID: 39149330 Free PMC article. Preprint.
Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Thathy V, Hackett F, Yeo T, Li VL, Muir R, Faucher F, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: lovell s. Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006. Epub 2024 Aug 12. Cell Chem Biol. 2024. PMID: 39137783
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display.
Lan T, Peng C, Yao X, Chan RST, Wei T, Rupanya A, Radakovic A, Wang S, Chen S, Lovell S, Snyder SA, Bogyo M, Dickinson BC. Lan T, et al. Among authors: lovell s. J Am Chem Soc. 2024 Aug 28;146(34):24053-24060. doi: 10.1021/jacs.4c07851. Epub 2024 Aug 13. J Am Chem Soc. 2024. PMID: 39136646
Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin.
Mahoney MW, Helander J, Kooner AS, Norman M, Damalanka VC, De Bona P, Kasperkiewicz P, Rut W, Poreba M, Kashipathy MM, Battaile KP, Lovell S, O'Donoghue AJ, Craik CS, Drag M, Janetka JW. Mahoney MW, et al. Among authors: lovell s. Protein Sci. 2024 Aug;33(8):e5110. doi: 10.1002/pro.5110. Protein Sci. 2024. PMID: 39073183
Crystal structures of NAD(P)H nitroreductases from Klebsiella pneumoniae.
Kancherla AD, Liu L, Tillery L, Shek R, Craig JK, Machen AJ, Seibold S, Battaile KP, Fradi S, Barrett LK, Subramanian S, Myler P, Van Voorhis WC, Lovell S. Kancherla AD, et al. Among authors: lovell s. Acta Crystallogr F Struct Biol Commun. 2024 Aug 1;80(Pt 8):173-182. doi: 10.1107/S2053230X24006472. Epub 2024 Jul 11. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38990055
Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies.
Dampalla CS, Kim Y, Zabiegala A, Howard DJ, Nguyen HN, Madden TK, Thurman HA, Cooper A, Liu L, Battaile KP, Lovell S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: lovell s. J Med Chem. 2024 Jul 25;67(14):11937-11956. doi: 10.1021/acs.jmedchem.4c00551. Epub 2024 Jul 2. J Med Chem. 2024. PMID: 38953866
369 results