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Page 1
Outcomes from the International Society of Nephrology Haemolytic Uraemic Syndromes International Forum.
Kavanagh D, Ardissino G, Brocklebank V, Bouwmeester RN, Bagga A, Ter Heine R, Johnson S, Licht C, Ma ALT, Noris M, Praga M, Rondeau E, Sinha A, Smith RJH, Sheerin NS, Trimarchi H, Wetzels JFM, Vivarelli M, Van de Kar NCAJ, Greenbaum LA; Forum Participants. Kavanagh D, et al. Among authors: brocklebank v. Kidney Int. 2024 Oct 10:S0085-2538(24)00705-1. doi: 10.1016/j.kint.2024.09.012. Online ahead of print. Kidney Int. 2024. PMID: 39395628
Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort.
Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Masoud S, Annear N, Barratt J, Bingham C, Coward RJ, Chrysochou T, Game D, Griffin S, Hall M, Johnson S, Kanigicherla D, Karet Frankl F, Kavanagh D, Kerecuk L, Maher ER, Moochhala S, Pinney J, Sayer JA, Simms R, Sinha S, Srivastava S, Tam FWK, Thomas K, Turner AN, Walsh SB, Waters A, Wilson P, Wong E, Sy KTL, Huang K, Ye J, Nitsch D, Saleem M, Bockenhauer D, Bramham K, Gale DP; RaDaR consortium. Wong K, et al. Kidney Int Rep. 2024 May 9;9(7):2067-2083. doi: 10.1016/j.ekir.2024.04.062. eCollection 2024 Jul. Kidney Int Rep. 2024. PMID: 39081723 Free PMC article.
Comprehensive functional characterization of complement factor I rare variant genotypes identified in the SCOPE geographic atrophy cohort.
Hallam TM, Andreadi A, Sharp SJ, Brocklebank V, Gardenal E, Dreismann A; SCOPE Study Group; Lotery AJ, Marchbank KJ, Harris CL, Jones AV, Kavanagh D. Hallam TM, et al. Among authors: brocklebank v. J Biol Chem. 2024 Jul;300(7):107452. doi: 10.1016/j.jbc.2024.107452. Epub 2024 Jun 7. J Biol Chem. 2024. PMID: 38852887 Free PMC article.
Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort.
Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Annear N, Barratt J, Bingham C, Chrysochou C, Coward RJ, Game D, Griffin S, Hall M, Johnson S, Kanigicherla D, Karet Frankl F, Kavanagh D, Kerecuk L, Maher ER, Moochhala S, Pinney J, Sayer JA, Simms R, Sinha S, Srivastava S, Tam FWK, Turner AN, Walsh SB, Waters A, Wilson P, Wong E, Taylor CM, Nitsch D, Saleem M, Bockenhauer D, Bramham K, Gale DP; RaDaR consortium. Wong K, et al. Lancet. 2024 Mar 30;403(10433):1279-1289. doi: 10.1016/S0140-6736(23)02843-X. Epub 2024 Mar 13. Lancet. 2024. PMID: 38492578 Free article.
A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.
Hallam TM, Cox TE, Smith-Jackson K, Brocklebank V, Baral AJ, Tzoumas N, Steel DH, Wong EKS, Shuttleworth VG, Lotery AJ, Harris CL, Marchbank KJ, Kavanagh D. Hallam TM, et al. Among authors: brocklebank v. Front Immunol. 2022 Dec 28;13:1028760. doi: 10.3389/fimmu.2022.1028760. eCollection 2022. Front Immunol. 2022. PMID: 36643920 Free PMC article.
Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome.
Glover EK, Smith-Jackson K, Brocklebank V, Wilson V, Walsh PR, Montgomery EK, Wong EKS, Johnson S, Malina M, Kavanagh D, Sheerin NS; UK aHUS Transplant Consortium. Glover EK, et al. Among authors: brocklebank v. Transplantation. 2023 Apr 1;107(4):994-1003. doi: 10.1097/TP.0000000000004355. Epub 2023 Mar 31. Transplantation. 2023. PMID: 36413152 Free PMC article.
Safety and impact of eculizumab withdrawal in patients with atypical haemolytic uraemic syndrome: protocol for a multicentre, open-label, prospective, single-arm study.
Dunn S, Brocklebank V, Bryant A, Carnell S, Chadwick TJ, Johnson S, Kavanagh D, Lecouturier J, Malina M, Moloney E, Oluboyede Y, Weetman C, Wong EKS, Woodward L, Sheerin N. Dunn S, et al. Among authors: brocklebank v. BMJ Open. 2022 Sep 19;12(9):e054536. doi: 10.1136/bmjopen-2021-054536. BMJ Open. 2022. PMID: 36123058 Free PMC article.
The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.
McMahon O, Hallam TM, Patel S, Harris CL, Menny A, Zelek WM, Widjajahakim R, Java A, Cox TE, Tzoumas N, Steel DHW, Shuttleworth VG, Smith-Jackson K, Brocklebank V, Griffiths H, Cree AJ, Atkinson JP, Lotery AJ, Bubeck D, Morgan BP, Marchbank KJ, Seddon JM, Kavanagh D. McMahon O, et al. Among authors: brocklebank v. Hum Mol Genet. 2021 Jun 17;30(13):1188-1199. doi: 10.1093/hmg/ddab086. Hum Mol Genet. 2021. PMID: 33783477 Free PMC article.
25 results