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Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9.
Eggers AR, Chen K, Soczek KM, Tuck OT, Doherty EE, Xu B, Trinidad MI, Thornton BW, Yoon PH, Doudna JA. Eggers AR, et al. Among authors: tuck ot. Cell. 2024 Jun 20;187(13):3249-3261.e14. doi: 10.1016/j.cell.2024.04.031. Epub 2024 May 22. Cell. 2024. PMID: 38781968 Free article.
Hachiman is a genome integrity sensor.
Tuck OT, Adler BA, Armbruster EG, Lahiri A, Hu JJ, Zhou J, Pogliano J, Doudna JA. Tuck OT, et al. bioRxiv [Preprint]. 2024 Feb 29:2024.02.29.582594. doi: 10.1101/2024.02.29.582594. bioRxiv. 2024. PMID: 38464307 Free PMC article. Preprint.
Genome expansion by a CRISPR trimmer-integrase.
Wang JY, Tuck OT, Skopintsev P, Soczek KM, Li G, Al-Shayeb B, Zhou J, Doudna JA. Wang JY, et al. Among authors: tuck ot. Nature. 2023 Jun;618(7966):855-861. doi: 10.1038/s41586-023-06178-2. Epub 2023 Jun 14. Nature. 2023. PMID: 37316664 Free PMC article.
Rubisco Function, Evolution, and Engineering.
Prywes N, Phillips NR, Tuck OT, Valentin-Alvarado LE, Savage DF. Prywes N, et al. Among authors: tuck ot. Annu Rev Biochem. 2023 Jun 20;92:385-410. doi: 10.1146/annurev-biochem-040320-101244. Epub 2023 Apr 26. Annu Rev Biochem. 2023. PMID: 37127263 Free article. Review.
Metabolic inhibitors of bacterial glycan biosynthesis.
Williams DA, Pradhan K, Paul A, Olin IR, Tuck OT, Moulton KD, Kulkarni SS, Dube DH. Williams DA, et al. Among authors: tuck ot. Chem Sci. 2020 Jan 8;11(7):1761-1774. doi: 10.1039/c9sc05955e. Chem Sci. 2020. PMID: 34123271 Free PMC article.