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Page 1
Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways.
Dai C, Zhang Y, Gong Y, Bradley A, Tang Z, Sellick K, Shrestha S, Spears E, Covington BA, Stanley J, Jenkins R, Richardson TM, Brantley RA, Coate K, Saunders DC, Wright JJ, Brissova M, Dean ED, Powers AC, Chen W. Dai C, et al. Among authors: powers ac. iScience. 2024 Nov 22;27(12):111447. doi: 10.1016/j.isci.2024.111447. eCollection 2024 Dec 20. iScience. 2024. PMID: 39720531 Free PMC article.
Heterogeneous endocrine cell composition defines human islet functional phenotypes.
Evans-Molina C, Pettway YD, Saunders DC, Sharp SA, Bate TS, Sun H, Durai H, Mei S, Coldren A, Davis C, Reihsmann CV, Hopkirk AL, Taylor J, Bradley A, Aramandla R, Poffenberger G, Eskaros A, Jenkins R, Shi D, Kang H, Rajesh V, Thaman S, Feng F, Cartailler JP, Powers AC, Abraham K, Gloyn AL, Niland JC, Brissova M. Evans-Molina C, et al. Among authors: powers ac. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.623809. doi: 10.1101/2024.11.20.623809. bioRxiv. 2024. PMID: 39605606 Free PMC article. Preprint.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Among authors: powers ac. Mol Metab. 2024 Dec;90:102050. doi: 10.1016/j.molmet.2024.102050. Epub 2024 Oct 20. Mol Metab. 2024. PMID: 39433176 Free PMC article.
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners.
Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Coate KC, et al. Among authors: powers ac. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606926. doi: 10.1101/2024.08.06.606926. bioRxiv. 2024. Update in: Mol Metab. 2024 Dec;90:102050. doi: 10.1016/j.molmet.2024.102050 PMID: 39149351 Free PMC article. Updated. Preprint.
CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets.
Wu X, Chen PI, Whitener RL, MacDougall MS, Coykendall VMN, Yan H, Kim YB, Harper W, Pathak S, Iliopoulou BP, Hestor A, Saunders DC, Spears E, Sévigny J, Maahs DM, Basina M, Sharp SA, Gloyn AL, Powers AC, Kim SK, Jensen KP, Meyer EH. Wu X, et al. Among authors: powers ac. Front Immunol. 2024 Jun 28;15:1415102. doi: 10.3389/fimmu.2024.1415102. eCollection 2024. Front Immunol. 2024. PMID: 39007132 Free PMC article.
227 results