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Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy.
Kang TG, Lan X, Mi T, Chen H, Alli S, Lim SE, Bhatara S, Vasandan AB, Ward G, Bentivegna S, Jang J, Spatz ML, Han JH, Schlotmann BC, Jespersen JS, Derenzo C, Vogel P, Yu J, Baylin S, Jones P, O'Connell C, Grønbæk K, Youngblood B, Zebley CC. Kang TG, et al. Among authors: zebley cc. Science. 2024 Oct 11;386(6718):eadl4492. doi: 10.1126/science.adl4492. Epub 2024 Oct 11. Science. 2024. PMID: 39388542
Conserved epigenetic hallmarks of T cell aging during immunity and malignancy.
Mi T, Soerens AG, Alli S, Kang TG, Vasandan AB, Wang Z, Vezys V, Kimura S, Iacobucci I, Baylin SB, Jones PA, Hiner C, Mueller A, Goldstein H, Mullighan CG, Zebley CC, Masopust D, Youngblood B. Mi T, et al. Among authors: zebley cc. Nat Aging. 2024 Aug;4(8):1053-1063. doi: 10.1038/s43587-024-00649-5. Epub 2024 Jun 12. Nat Aging. 2024. PMID: 38867059 Free PMC article.
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion.
Lamarche C, Ward-Hartstonge K, Mi T, Lin DTS, Huang Q, Brown A, Edwards K, Novakovsky GE, Qi CN, Kobor MS, Zebley CC, Weber EW, Mackall CL, Levings MK. Lamarche C, et al. Among authors: zebley cc. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2219086120. doi: 10.1073/pnas.2219086120. Epub 2023 Mar 27. Proc Natl Acad Sci U S A. 2023. PMID: 36972454 Free PMC article.
Tapping the keg of discovery to advance T cell therapy.
Schulz AM, Zebley CC, Youngblood B, Zehn D. Schulz AM, et al. Among authors: zebley cc. Nat Immunol. 2023 Feb;24(2):213-215. doi: 10.1038/s41590-022-01401-0. Nat Immunol. 2023. PMID: 36631639 Free PMC article.
Improving antitumor T cells.
Zebley CC, Youngblood B. Zebley CC, et al. Science. 2022 Nov 11;378(6620):598. doi: 10.1126/science.adf0546. Epub 2022 Nov 10. Science. 2022. PMID: 36356156
21 results