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Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Tse EG, Stashko MA, Li K, Norris-Drouin JL, Herring LE, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith CH, Couñago RM, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise MT, Willson TM, Popov KI, Pearce KH. Merten EM, et al. Among authors: heise mt. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073/pnas.2409166121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388272
γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease.
Long KM, Ferris MT, Whitmore AC, Montgomery SA, Thurlow LR, McGee CE, Rodriguez CA, Lim JK, Heise MT. Long KM, et al. Among authors: heise mt. J Virol. 2015 Oct 21;90(1):433-43. doi: 10.1128/JVI.02159-15. Print 2016 Jan 1. J Virol. 2015. PMID: 26491151 Free PMC article.
Chikungunya Virus: Current Perspectives on a Reemerging Virus.
Morrison CR, Plante KS, Heise MT. Morrison CR, et al. Among authors: heise mt. Microbiol Spectr. 2016 Jun;4(3):10.1128/microbiolspec.EI10-0017-2016. doi: 10.1128/microbiolspec.EI10-0017-2016. Microbiol Spectr. 2016. PMID: 27337473 Free PMC article. Review.
Animal Models of Chikungunya Virus Infection and Disease.
Haese NN, Broeckel RM, Hawman DW, Heise MT, Morrison TE, Streblow DN. Haese NN, et al. Among authors: heise mt. J Infect Dis. 2016 Dec 15;214(suppl 5):S482-S487. doi: 10.1093/infdis/jiw284. J Infect Dis. 2016. PMID: 27920178 Free PMC article. Review.
Structural divergence creates new functional features in alphavirus genomes.
Kutchko KM, Madden EA, Morrison C, Plante KS, Sanders W, Vincent HA, Cruz Cisneros MC, Long KM, Moorman NJ, Heise MT, Laederach A. Kutchko KM, et al. Among authors: heise mt. Nucleic Acids Res. 2018 Apr 20;46(7):3657-3670. doi: 10.1093/nar/gky012. Nucleic Acids Res. 2018. PMID: 29361131 Free PMC article.
Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs.
Broeckel R, Sarkar S, May NA, Totonchy J, Kreklywich CN, Smith P, Graves L, DeFilippis VR, Heise MT, Morrison TE, Moorman N, Streblow DN. Broeckel R, et al. Among authors: heise mt. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02325-18. doi: 10.1128/AAC.02325-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30917980 Free PMC article.
163 results