Eichner LJ - Search Results

1

Transcriptional repression by HDAC3 mediates T cell exclusion from Kras mutant lung tumors.

McGuire CK, Meehan AS, Couser E, Bull L, Minor AC, Kuhlmann-Hogan A, Kaech SM, Shaw RJ, Eichner LJ. McGuire CK, et al. Among authors: eichner lj. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2317694121. doi: 10.1073/pnas.2317694121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388266

2

HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non-small cell lung cancer.

Eichner LJ, Curtis SD, Brun SN, McGuire CK, Gushterova I, Baumgart JT, Trefts E, Ross DS, Rymoff TJ, Shaw RJ. Eichner LJ, et al. Sci Adv. 2023 Mar 15;9(11):eadd3243. doi: 10.1126/sciadv.add3243. Epub 2023 Mar 17. Sci Adv. 2023. PMID: 36930718 Free PMC article.

3

The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer.

Rodón L, Svensson RU, Wiater E, Chun MGH, Tsai WW, Eichner LJ, Shaw RJ, Montminy M. Rodón L, et al. Among authors: eichner lj. Sci Adv. 2019 Jul 24;5(7):eaaw6455. doi: 10.1126/sciadv.aaw6455. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31355336 Free PMC article.

4

The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC.

Hollstein PE, Eichner LJ, Brun SN, Kamireddy A, Svensson RU, Vera LI, Ross DS, Rymoff TJ, Hutchins A, Galvez HM, Williams AE, Shokhirev MN, Screaton RA, Berdeaux R, Shaw RJ. Hollstein PE, et al. Among authors: eichner lj. Cancer Discov. 2019 Nov;9(11):1606-1627. doi: 10.1158/2159-8290.CD-18-1261. Epub 2019 Jul 26. Cancer Discov. 2019. PMID: 31350328 Free PMC article.

5

Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models.

Eichner LJ, Brun SN, Herzig S, Young NP, Curtis SD, Shackelford DB, Shokhirev MN, Leblanc M, Vera LI, Hutchins A, Ross DS, Shaw RJ, Svensson RU. Eichner LJ, et al. Cell Metab. 2019 Feb 5;29(2):285-302.e7. doi: 10.1016/j.cmet.2018.10.005. Epub 2018 Nov 8. Cell Metab. 2019. PMID: 30415923 Free PMC article.

6

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.

Svensson RU, Parker SJ, Eichner LJ, Kolar MJ, Wallace M, Brun SN, Lombardo PS, Van Nostrand JL, Hutchins A, Vera L, Gerken L, Greenwood J, Bhat S, Harriman G, Westlin WF, Harwood HJ Jr, Saghatelian A, Kapeller R, Metallo CM, Shaw RJ. Svensson RU, et al. Among authors: eichner lj. Nat Med. 2016 Oct;22(10):1108-1119. doi: 10.1038/nm.4181. Epub 2016 Sep 19. Nat Med. 2016. PMID: 27643638 Free PMC article.

7

AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes.

Young NP, Kamireddy A, Van Nostrand JL, Eichner LJ, Shokhirev MN, Dayn Y, Shaw RJ. Young NP, et al. Among authors: eichner lj. Genes Dev. 2016 Mar 1;30(5):535-52. doi: 10.1101/gad.274142.115. Genes Dev. 2016. PMID: 26944679 Free PMC article.

8

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Perry MC, Dufour CR, Eichner LJ, Tsang DW, Deblois G, Muller WJ, Giguère V. Perry MC, et al. Among authors: eichner lj. Mol Cell Biol. 2014 Dec 1;34(23):4232-43. doi: 10.1128/MCB.00895-14. Epub 2014 Sep 22. Mol Cell Biol. 2014. PMID: 25246633 Free PMC article.

9

Transcriptional coregulators: fine-tuning metabolism.

Mouchiroud L, Eichner LJ, Shaw RJ, Auwerx J. Mouchiroud L, et al. Among authors: eichner lj. Cell Metab. 2014 Jul 1;20(1):26-40. doi: 10.1016/j.cmet.2014.03.027. Epub 2014 May 1. Cell Metab. 2014. PMID: 24794975 Free PMC article. Review.

10

Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver.

Chaveroux C, Eichner LJ, Dufour CR, Shatnawi A, Khoutorsky A, Bourque G, Sonenberg N, Giguère V. Chaveroux C, et al. Among authors: eichner lj. Cell Metab. 2013 Apr 2;17(4):586-98. doi: 10.1016/j.cmet.2013.03.003. Cell Metab. 2013. PMID: 23562079 Free article.

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