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Page 1
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses.
Trifinopoulos J, List J, Klampfl T, Klein K, Prchal-Murphy M, Witalisz-Siepracka A, Bellutti F, Fava LL, Heller G, Stummer S, Testori P, Den Boer ML, Boer JM, Marinovic S, Hoermann G, Walter W, Villunger A, Sicinski P, Sexl V, Gotthardt D. Trifinopoulos J, et al. Among authors: fava ll. Haematologica. 2024 Oct 10. doi: 10.3324/haematol.2024.285701. Online ahead of print. Haematologica. 2024. PMID: 39385738 Free article.
Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest.
Pavani M, Chiroli E, Cancrini C, Gross F, Bonaiuti P, Villa S, Giavazzi F, Matafora V, Bachi A, Fava LL, Lischetti T, Ciliberto A. Pavani M, et al. Among authors: fava ll. Cell Rep. 2023 Mar 28;42(3):112215. doi: 10.1016/j.celrep.2023.112215. Epub 2023 Mar 13. Cell Rep. 2023. PMID: 36917609 Free article.
Caspase-2 kills cells with extra centrosomes.
Rizzotto D, Vigorito V, Rieder P, Gallob F, Moretta GM, Soratroi C, Riley JS, Bellutti F, Veli SL, Mattivi A, Lohmüller M, Herzog S, Bornhauser BC, Jacotot ED, Villunger A, Fava LL. Rizzotto D, et al. Among authors: fava ll. Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475598 Free PMC article.
Targeting ATP2B1 impairs PI3K/Akt/FOXO signaling and reduces SARS-COV-2 infection and replication.
de Antonellis P, Ferrucci V, Miceli M, Bibbo F, Asadzadeh F, Gorini F, Mattivi A, Boccia A, Russo R, Andolfo I, Lasorsa VA, Cantalupo S, Fusco G, Viscardi M, Brandi S, Cerino P, Monaco V, Choi DR, Cheong JH, Iolascon A, Amente S, Monti M, Fava LL, Capasso M, Kim HY, Zollo M. de Antonellis P, et al. Among authors: fava ll. EMBO Rep. 2024 Jul;25(7):2974-3007. doi: 10.1038/s44319-024-00164-z. Epub 2024 May 30. EMBO Rep. 2024. PMID: 38816514 Free PMC article.
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Wang Z, et al. Among authors: fava ll. Cancer Discov. 2024 Feb 8;14(2):362-379. doi: 10.1158/2159-8290.CD-23-0402. Cancer Discov. 2024. PMID: 37877779 Free PMC article.
Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance.
Garcia-Carpio I, Braun VZ, Weiler ES, Leone M, Niñerola S, Barco A, Fava LL, Villunger A. Garcia-Carpio I, et al. Among authors: fava ll. EMBO J. 2023 Oct 16;42(20):e113510. doi: 10.15252/embj.2023113510. Epub 2023 Aug 2. EMBO J. 2023. PMID: 37530438 Free PMC article.
33 results