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266 results

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Page 1
Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating.
Liu P, Pan Y, Chang HC, Wang W, Fang Y, Xue X, Zou J, Toothaker JM, Olaloye O, Santiago EG, McCourt B, Mitsialis V, Presicce P, Kallapur SG, Snapper SB, Liu JJ, Tseng GC, Konnikova L, Liu S. Liu P, et al. Among authors: snapper sb. Brief Bioinform. 2024 Nov 22;26(1):bbae633. doi: 10.1093/bib/bbae633. Brief Bioinform. 2024. PMID: 39656848 Free PMC article.
Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes.
French CE, Andrews NC, Beggs AH, Boone PM, Brownstein CA, Chopra M, Chou J, Chung WK, D'Gama AM, Doan RN, Ebrahimi-Fakhari D, Goldstein RD, Irons M, Jacobsen C, Kenna M, Lee T, Madden JA, Majmundar AJ, Mann N, Morton SU, Poduri A, Randolph AG, Roberts AE, Roberts S, Sampson MG, Shao DD, Shao W, Sharma A, Shearer E, Shimamura A, Snapper SB, Srivastava S, Thiagarajah JR, Whitman MC, Wojcik MH, Rockowitz S, Sliz P. French CE, et al. Among authors: snapper sb. NPJ Genom Med. 2024 Dec 2;9(1):60. doi: 10.1038/s41525-024-00441-9. NPJ Genom Med. 2024. PMID: 39622807 Free PMC article.
Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.
Ghasempour S, Warner N, Guan R, Rodari MM, Ivanochko D, Whittaker Hawkins R, Marwaha A, Nowak JK, Liang Y, Mulder DJ, Stallard L, Li M, Yu DD, Pluthero FG, Batura V, Zhao M, Siddiqui I, Upton JEM, Hulst JM, Kahr WHA, Mendoza-Londono R, Charbit-Henrion F, Hoefsloot LH, Khiat A, Moreira D, Trindade E, Espinheira MDC, Pinto Pais I, Weerts MJA, Douben H, Kotlarz D, Snapper SB, Klein C, Dowling JJ, Julien JP, Joosten M, Cerf-Bensussan N, Freeman SA, Parlato M, van Ham TJ, Muise AM. Ghasempour S, et al. Among authors: snapper sb. J Exp Med. 2024 Dec 2;221(12):e20240546. doi: 10.1084/jem.20240546. Epub 2024 Nov 11. J Exp Med. 2024. PMID: 39526957 Free PMC article.
Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Jena KK, Mambu J, Boehmer D, Sposito B, Millet V, de Sousa Casal J, Muendlein HI, Spreafico R, Fenouil R, Spinelli L, Wurbel S, Riquier C, Galland F, Naquet P, Chasson L, Elkins M, Mitsialis V, Ketelut-Carneiro N, Bugda Gwilt K, Thiagarajah JR, Ruan HB, Lin Z, Lien E, Shao F, Chou J, Poltorak A, Ordovas-Montanes J, Fitzgerald KA, Snapper SB, Broggi A, Zanoni I. Jena KK, et al. Among authors: snapper sb. Cell. 2024 Nov 4:S0092-8674(24)01158-9. doi: 10.1016/j.cell.2024.10.010. Online ahead of print. Cell. 2024. PMID: 39500322
Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Lee SH, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K; Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium; Abreu M, Beck P, Bernstein C, Croitoru K, Dieleman L, Feagan B, Griffiths A, Guttman D, Jacobson K, Kaplan G, Krause DO, Madsen K, Marshall J, Moayyedi P, Ropeleski M, Seidman E, Silverberg M, Snapper S, Stadnyk A, Steinhart AH, Surette M, Turner D, Walters T, Vallance B, Aumais G, Bitton A, Cino M, Critch J, Denson L, Deslandres C, El-Matary W, Herfarth H, Higgins P, Huynh HQ, Hyams J, Mack D, McGrath J, Otley A, Panancionne R, Abreu M, Aumais G, Baldassano R, Bernstein C, Cino M, Denson L, Deslandres C, El-Matary W, Griffiths AM, Hedin C, Herfarth H, Higgins P, Hussey S, Huynh HQ, Jacobson K, Keljo D, Kevans D, Lees C, Mack D, Marshall J, McGrath J, Murthy S, Otley A, Panaccione R, Parekh N, Plamondon S, Radford-Smith G, Ropeleski M, Rosh J, Rubin D, Schultz M, Seidman E, Siegel C, Snapper S, Steinhart AH, Turner D. Lee SH, et al. Among authors: snapper s. Gastroenterology. 2024 Oct 9:S0016-5085(24)05539-2. doi: 10.1053/j.gastro.2024.09.033. Online ahead of print. Gastroenterology. 2024. PMID: 39384162 Free article. No abstract available.
Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease.
Olivera PA, Martinez-Lozano H, Leibovitzh H, Xue M, Neustaeter A, Espin-Garcia O, Xu W, Madsen KL, Guttman DS, Bernstein CN, Yerushalmi B, Hyams JS, Abreu MT, Marshall JK, Wrobel I, Mack DR, Jacobson K, Bitton A, Aumais G, Panacionne R, Dieleman LA, Silverberg MS, Steinhart AH, Moayyedi P, Turner D, Griffiths AM, Turpin W, Lee SH, Croitoru K; Crohn’s and Colitis Canada (CCC) Genetic, Environmental, Microbial (GEM) Project Research Consortium. Olivera PA, et al. Gastroenterology. 2025 Jan;168(1):99-110.e2. doi: 10.1053/j.gastro.2024.08.031. Epub 2024 Sep 3. Gastroenterology. 2025. PMID: 39236898 Free article.
Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study.
Lee SH, Turpin W, Espin-Garcia O, Xu W, Croitoru K; Crohn's and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium. Lee SH, et al. Gastroenterology. 2025 Jan;168(1):150-153.e4. doi: 10.1053/j.gastro.2024.08.021. Epub 2024 Aug 30. Gastroenterology. 2025. PMID: 39209122 Free article. No abstract available.
266 results