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117 results

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Page 1
A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification.
Rosen LE, Tortorici MA, De Marco A, Pinto D, Foreman WB, Taylor AL, Park YJ, Bohan D, Rietz T, Errico JM, Hauser K, Dang HV, Chartron JW, Giurdanella M, Cusumano G, Saliba C, Zatta F, Sprouse KR, Addetia A, Zepeda SK, Brown J, Lee J, Dellota E Jr, Rajesh A, Noack J, Tao Q, DaCosta Y, Tsu B, Acosta R, Subramanian S, de Melo GD, Kergoat L, Zhang I, Liu Z, Guarino B, Schmid MA, Schnell G, Miller JL, Lempp FA, Czudnochowski N, Cameroni E, Whelan SPJ, Bourhy H, Purcell LA, Benigni F, di Iulio J, Pizzuto MS, Lanzavecchia A, Telenti A, Snell G, Corti D, Veesler D, Starr TN. Rosen LE, et al. Among authors: tortorici ma. Cell. 2024 Dec 12;187(25):7196-7213.e26. doi: 10.1016/j.cell.2024.09.026. Epub 2024 Oct 8. Cell. 2024. PMID: 39383863 Free PMC article.
Broadly neutralizing antibodies against emerging delta-coronaviruses.
Rexhepaj M, Park YJ, Perruzza L, Asarnow D, Mccallum M, Culap K, Saliba C, Leoni G, Balmelli A, Yoshiyama CN, Dickinson MS, Quispe J, Brown JT, Tortorici MA, Sprouse KR, Taylor AL, Starr TN, Corti D, Benigni F, Veesler D. Rexhepaj M, et al. Among authors: tortorici ma. bioRxiv [Preprint]. 2024 Apr 1:2024.03.27.586411. doi: 10.1101/2024.03.27.586411. bioRxiv. 2024. Update in: Immunity. 2024 Dec 10;57(12):2914-2927.e7. doi: 10.1016/j.immuni.2024.10.001 PMID: 38617231 Free PMC article. Updated. Preprint.
Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.
McCallum M, Park YJ, Stewart C, Sprouse KR, Addetia A, Brown J, Tortorici MA, Gibson C, Wong E, Ieven M, Telenti A, Veesler D. McCallum M, et al. Among authors: tortorici ma. Cell. 2024 Aug 8;187(16):4231-4245.e13. doi: 10.1016/j.cell.2024.06.006. Epub 2024 Jul 3. Cell. 2024. PMID: 38964328 Free article.
A pan-variant miniprotein inhibitor protects against SARS-CoV-2 variants.
Lee J, Case JB, Park YJ, Ravichandran R, Asarnow D, Tortorici MA, Brown JT, Sanapala S, Carter L, Baker D, Diamond MS, Veesler D. Lee J, et al. Among authors: tortorici ma. bioRxiv [Preprint]. 2024 Aug 10:2024.08.08.606885. doi: 10.1101/2024.08.08.606885. bioRxiv. 2024. PMID: 39149384 Free PMC article. Preprint.
Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses.
Rexhepaj M, Asarnow D, Perruzza L, Park YJ, Guarino B, Mccallum M, Culap K, Saliba C, Leoni G, Balmelli A, Yoshiyama CN, Dickinson MS, Quispe J, Brown JT, Tortorici MA, Sprouse KR, Taylor AL, Corti D, Starr TN, Benigni F, Veesler D. Rexhepaj M, et al. Among authors: tortorici ma. Immunity. 2024 Dec 10;57(12):2914-2927.e7. doi: 10.1016/j.immuni.2024.10.001. Epub 2024 Nov 1. Immunity. 2024. PMID: 39488210 Free article.
Designed miniproteins potently inhibit and protect against MERS-CoV.
Ragotte RJ, Tortorici MA, Catanzaro NJ, Addetia A, Coventry B, Froggatt HM, Lee J, Stewart C, Brown JT, Goreshnik I, Sims JN, Milles LF, Wicky BIM, Glögl M, Gerben S, Kang A, Bera AK, Sharkey W, Schäfer A, Baric RS, Baker D, Veesler D. Ragotte RJ, et al. Among authors: tortorici ma. bioRxiv [Preprint]. 2024 Nov 4:2024.11.03.621760. doi: 10.1101/2024.11.03.621760. bioRxiv. 2024. PMID: 39574666 Free PMC article. Preprint.
First-in-human study evaluating safety, pharmacokinetics, and pharmacodynamics of lorundrostat, a novel and highly selective aldosterone synthase inhibitor.
Shimizu H, Tortorici MA, Ohta Y, Ogawa K, Rahman SMA, Fujii A, Hiraga Y, Kawai M, Sugimoto-Kawabata K, van Iersel MT, van Lier JJ, Djedjos S, Slingsby BT, Rodman DM. Shimizu H, et al. Among authors: tortorici ma. Clin Transl Sci. 2024 Aug;17(8):e70000. doi: 10.1111/cts.70000. Clin Transl Sci. 2024. PMID: 39152532 Free PMC article. Clinical Trial.
Human coronavirus HKU1 recognition of the TMPRSS2 host receptor.
McCallum M, Park YJ, Stewart C, Sprouse KR, Brown J, Tortorici MA, Gibson C, Wong E, Ieven M, Telenti A, Veesler D. McCallum M, et al. Among authors: tortorici ma. bioRxiv [Preprint]. 2024 Jan 9:2024.01.09.574565. doi: 10.1101/2024.01.09.574565. bioRxiv. 2024. Update in: Cell. 2024 Aug 8;187(16):4231-4245.e13. doi: 10.1016/j.cell.2024.06.006 PMID: 38260518 Free PMC article. Updated. Preprint.
117 results