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Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity.
Oxley EP, Kershaw NJ, Louis C, Goodall KJ, Garwood MM, Jee Ho SM, Voo VTF, Park HY, Iaria J, Wong LLL, Lebenbaum AG, Wiranata S, Pang ES, Edwards ESJ, D'Silva DB, Hansen J, van Zelm MC, O'Keeffe M, Hogarth PM, Haynes NM, Huntington ND, Wicks IP, Dickins RA. Oxley EP, et al. Among authors: wicks ip. Cell Rep. 2024 Oct 22;43(10):114834. doi: 10.1016/j.celrep.2024.114834. Epub 2024 Oct 8. Cell Rep. 2024. PMID: 39383033 Free article.
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis.
Dragoljevic D, Lee MKS, Pernes G, Morgan PK, Louis C, Shihata W, Huynh K, Kochetkova AA, Bell PW, Mellett NA, Meikle PJ, Lancaster GI, Kraakman MJ, Nagareddy PR, Hanaoka BY, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: wicks ip. Clin Transl Immunology. 2023 Apr 18;12(4):e1446. doi: 10.1002/cti2.1446. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37091327 Free PMC article.
An immunohistochemical atlas of necroptotic pathway expression.
Chiou S, Al-Ani AH, Pan Y, Patel KM, Kong IY, Whitehead LW, Light A, Young SN, Barrios M, Sargeant C, Rajasekhar P, Zhu L, Hempel A, Lin A, Rickard JA, Hall C, Gangatirkar P, Yip RK, Cawthorne W, Jacobsen AV, Horne CR, Martin KR, Ioannidis LJ, Hansen DS, Day J, Wicks IP, Law C, Ritchie ME, Bowden R, Hildebrand JM, O'Reilly LA, Silke J, Giulino-Roth L, Tsui E, Rogers KL, Hawkins ED, Christensen B, Murphy JM, Samson AL. Chiou S, et al. Among authors: wicks ip. EMBO Mol Med. 2024 Jul;16(7):1717-1749. doi: 10.1038/s44321-024-00074-6. Epub 2024 May 15. EMBO Mol Med. 2024. PMID: 38750308 Free PMC article.
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation.
Garnish SE, Martin KR, Kauppi M, Jackson VE, Ambrose R, Eng VV, Chiou S, Meng Y, Frank D, Tovey Crutchfield EC, Patel KM, Jacobsen AV, Atkin-Smith GK, Di Rago L, Doerflinger M, Horne CR, Hall C, Young SN, Cook M, Athanasopoulos V, Vinuesa CG, Lawlor KE, Wicks IP, Ebert G, Ng AP, Slade CA, Pearson JS, Samson AL, Silke J, Murphy JM, Hildebrand JM. Garnish SE, et al. Among authors: wicks ip. Nat Commun. 2023 Sep 28;14(1):6046. doi: 10.1038/s41467-023-41724-6. Nat Commun. 2023. PMID: 37770424 Free PMC article.
149 results