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Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity.
Oxley EP, Kershaw NJ, Louis C, Goodall KJ, Garwood MM, Jee Ho SM, Voo VTF, Park HY, Iaria J, Wong LLL, Lebenbaum AG, Wiranata S, Pang ES, Edwards ESJ, D'Silva DB, Hansen J, van Zelm MC, O'Keeffe M, Hogarth PM, Haynes NM, Huntington ND, Wicks IP, Dickins RA. Oxley EP, et al. Among authors: louis c. Cell Rep. 2024 Oct 22;43(10):114834. doi: 10.1016/j.celrep.2024.114834. Epub 2024 Oct 8. Cell Rep. 2024. PMID: 39383033 Free article.
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Balka KR, Louis C, Saunders TL, Smith AM, Calleja DJ, D'Silva DB, Moghaddas F, Tailler M, Lawlor KE, Zhan Y, Burns CJ, Wicks IP, Miner JJ, Kile BT, Masters SL, De Nardo D. Balka KR, et al. Among authors: louis c. Cell Rep. 2020 Apr 7;31(1):107492. doi: 10.1016/j.celrep.2020.03.056. Cell Rep. 2020. PMID: 32268090 Free article.
Natural killer cells in inflammatory autoimmune diseases.
Yang Y, Day J, Souza-Fonseca Guimaraes F, Wicks IP, Louis C. Yang Y, et al. Among authors: louis c. Clin Transl Immunology. 2021 Feb 1;10(2):e1250. doi: 10.1002/cti2.1250. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33552511 Free PMC article. Review.
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia.
Carrington EM, Louis C, Kratina T, Hancock M, Keenan CR, Iannarella N, Allan RS, Wardak AZ, Czabotar PE, Herold MJ, Schenk RL, White CA, D'Silva D, Yang Y, Wong W, Wong H, Bryant VL, Huntington ND, Rautela J, Sutherland RM, Zhan Y, Hansen J, Nhu D, Lessene G, Wicks IP, Lew AM. Carrington EM, et al. Among authors: louis c. Blood Adv. 2021 Jun 8;5(11):2550-2562. doi: 10.1182/bloodadvances.2020004139. Blood Adv. 2021. PMID: 34100903 Free PMC article.
Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis.
Gangoda L, Schenk RL, Best SA, Nedeva C, Louis C, D'Silva DB, Fairfax K, Jarnicki AG, Puthalakath H, Sutherland KD, Strasser A, Herold MJ. Gangoda L, et al. Among authors: louis c. Cell Death Differ. 2022 Jan;29(1):96-104. doi: 10.1038/s41418-021-00839-3. Epub 2021 Jul 24. Cell Death Differ. 2022. PMID: 34304242 Free PMC article.
Emerging roles for IL-11 in inflammatory diseases.
Fung KY, Louis C, Metcalfe RD, Kosasih CC, Wicks IP, Griffin MDW, Putoczki TL. Fung KY, et al. Among authors: louis c. Cytokine. 2022 Jan;149:155750. doi: 10.1016/j.cyto.2021.155750. Epub 2021 Oct 22. Cytokine. 2022. PMID: 34689057 Free article. Review.
Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis.
Dragoljevic D, Lee MKS, Louis C, Shihata W, Kraakman MJ, Hansen J, Masters SL, Hanaoka BY, Nagareddy PR, Lancaster GI, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: louis c. Clin Transl Immunology. 2020 Nov 9;9(11):e1206. doi: 10.1002/cti2.1206. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33204425 Free PMC article.
633 results