Ahmed SF - Search Results

1

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids.

Dearlove EL, Chatrin C, Buetow L, Ahmed SF, Schmidt T, Bushell M, Smith BO, Huang DT. Dearlove EL, et al. Among authors: ahmed sf. Elife. 2024 Oct 8;13:RP98070. doi: 10.7554/eLife.98070. Elife. 2024. PMID: 39377462 Free PMC article.

2

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.

Ahmed SF, Buetow L, Gabrielsen M, Lilla S, Chatrin C, Sibbet GJ, Zanivan S, Huang DT. Ahmed SF, et al. Sci Adv. 2020 Aug 21;6(34):eabc0629. doi: 10.1126/sciadv.abc0629. Print 2020 Aug. Sci Adv. 2020. PMID: 32937373 Free PMC article.

3

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.

Chatrin C, Gabrielsen M, Buetow L, Nakasone MA, Ahmed SF, Sumpton D, Sibbet GJ, Smith BO, Huang DT. Chatrin C, et al. Among authors: ahmed sf. Sci Adv. 2020 Sep 18;6(38):eabc0418. doi: 10.1126/sciadv.abc0418. Print 2020 Sep. Sci Adv. 2020. PMID: 32948590 Free PMC article.

4

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.

Gabrielsen M, Buetow L, Nakasone MA, Ahmed SF, Sibbet GJ, Smith BO, Zhang W, Sidhu SS, Huang DT. Gabrielsen M, et al. Among authors: ahmed sf. Mol Cell. 2017 Oct 19;68(2):456-470.e10. doi: 10.1016/j.molcel.2017.09.027. Mol Cell. 2017. PMID: 29053960 Free PMC article.

5

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.

Buetow L, Tria G, Ahmed SF, Hock A, Dou H, Sibbet GJ, Svergun DI, Huang DT. Buetow L, et al. Among authors: ahmed sf. BMC Biol. 2016 Sep 8;14(1):76. doi: 10.1186/s12915-016-0298-6. BMC Biol. 2016. PMID: 27609087 Free PMC article.

6

E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis.

Ahmed SF, Buetow L, Gabrielsen M, Lilla S, Sibbet GJ, Sumpton D, Zanivan S, Hedley A, Clark W, Huang DT. Ahmed SF, et al. Oncogene. 2021 Mar;40(12):2149-2164. doi: 10.1038/s41388-021-01684-x. Epub 2021 Feb 24. Oncogene. 2021. PMID: 33627783 Free PMC article.

7

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.

Magnussen HM, Ahmed SF, Sibbet GJ, Hristova VA, Nomura K, Hock AK, Archibald LJ, Jamieson AG, Fushman D, Vousden KH, Weissman AM, Huang DT. Magnussen HM, et al. Among authors: ahmed sf. Nat Commun. 2020 Apr 29;11(1):2094. doi: 10.1038/s41467-020-15783-y. Nat Commun. 2020. PMID: 32350255 Free PMC article.

8

The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.

Paul I, Ahmed SF, Bhowmik A, Deb S, Ghosh MK. Paul I, et al. Among authors: ahmed sf. Oncogene. 2013 Mar 7;32(10):1284-95. doi: 10.1038/onc.2012.144. Epub 2012 Apr 30. Oncogene. 2013. PMID: 22543587

9

The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation.

Ahmed SF, Deb S, Paul I, Chatterjee A, Mandal T, Chatterjee U, Ghosh MK. Ahmed SF, et al. J Biol Chem. 2012 May 4;287(19):15996-6006. doi: 10.1074/jbc.M111.321083. Epub 2012 Mar 15. J Biol Chem. 2012. PMID: 22427670 Free PMC article.

10

Exosome-mediated delivery of the intrinsic C-terminus domain of PTEN protects it from proteasomal degradation and ablates tumorigenesis.

Ahmed SF, Das N, Sarkar M, Chatterjee U, Chatterjee S, Ghosh MK. Ahmed SF, et al. Mol Ther. 2015 Feb;23(2):255-69. doi: 10.1038/mt.2014.202. Epub 2014 Oct 20. Mol Ther. 2015. PMID: 25327178 Free PMC article.

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