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Page 1
Genetic architecture reconciles linkage and association studies of complex traits.
Sidorenko J, Couvy-Duchesne B, Kemper KE, Moen GH, Bhatta L, Åsvold BO, Mägi R; Estonian Biobank Research Team; Ani A, Wang R, Nolte IM; Lifelines Cohort Study; Gordon S, Hayward C, Campbell A, Benjamin DJ, Cesarini D, Evans DM, Goddard ME, Haley CS, Porteous D, Medland SE, Martin NG, Snieder H, Metspalu A, Hveem K, Brumpton B, Visscher PM, Yengo L. Sidorenko J, et al. Among authors: ani a. Nat Genet. 2024 Nov;56(11):2352-2360. doi: 10.1038/s41588-024-01940-2. Epub 2024 Oct 7. Nat Genet. 2024. PMID: 39375568
A saturated map of common genetic variants associated with human height.
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K, Lüll K, Malden DE, Medina-Gomez C, Machado M, Moore A, Rüeger S, Sim X, Vrieze S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J, Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai Q, Campbell A, Cañadas-Garre M, Catamo E, Chai JF, Chai X, Chang LC, Chang YC, Chen CH, Chesi A, Choi SH, Chung RH, Cocca M, Concas MP, Couture C, Cuellar-Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A, Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB, Engmann JE, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, He J, Heard-Co… See abstract for full author list ➔ Yengo L, et al. Among authors: ani a. Nature. 2022 Oct;610(7933):704-712. doi: 10.1038/s41586-022-05275-y. Epub 2022 Oct 12. Nature. 2022. PMID: 36224396 Free PMC article.
Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries.
Zheng Z, Liu S, Sidorenko J, Wang Y, Lin T, Yengo L, Turley P, Ani A, Wang R, Nolte IM, Snieder H; LifeLines Cohort Study; Yang J, Wray NR, Goddard ME, Visscher PM, Zeng J. Zheng Z, et al. Among authors: ani a. Nat Genet. 2024 May;56(5):767-777. doi: 10.1038/s41588-024-01704-y. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689000 Free PMC article.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, De Borst MH, Polašek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poul… See abstract for full author list ➔ Keaton JM, et al. Among authors: ani a. Nat Genet. 2024 May;56(5):778-791. doi: 10.1038/s41588-024-01714-w. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689001 Free PMC article.
Increased genetic contribution to wellbeing during the COVID-19 pandemic.
Warmerdam CAR, Wiersma HH, Lanting P, Ani A; Lifelines Corona Research Initiative; Lifelines Cohort Study; Dijkema MXL, Snieder H, Vonk JM, Boezen HM, Deelen P, Franke LH. Warmerdam CAR, et al. Among authors: ani a. PLoS Genet. 2022 May 19;18(5):e1010135. doi: 10.1371/journal.pgen.1010135. eCollection 2022 May. PLoS Genet. 2022. PMID: 35588108 Free PMC article.
A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals.
Lu X, van der Meer TP, Kamali Z, van Faassen M, Kema IP, van Beek AP, Xu X, Huo X, Ani A; Lifelines Cohort Study; Nolte IM, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV, Snieder H. Lu X, et al. Among authors: ani a. Environ Int. 2024 Jan;183:108396. doi: 10.1016/j.envint.2023.108396. Epub 2023 Dec 20. Environ Int. 2024. PMID: 38150807 Free article.
Corrigendum to "A genome-wide association study of 24-hour urinary excretion of endocrine disrupting chemicals" [Environ. Int., A Genome-Wide Association Study of 24-Hour Urinary Excretion of Endocrine Disrupting Chemicals 183 (2024) 108396].
Lu X, van der Meer TP, Kamali Z, van Faassen M, Kema IP, van Beek AP, Xu X, Huo X, Ani A; Lifelines Cohort Study; Nolte IM, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV, Snieder H. Lu X, et al. Among authors: ani a. Environ Int. 2024 Apr;186:108622. doi: 10.1016/j.envint.2024.108622. Epub 2024 Apr 5. Environ Int. 2024. PMID: 38582682 Free article. No abstract available.
327 results