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Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView.
Kudo T, Meireles AM, Moncada R, Chen Y, Wu P, Gould J, Hu X, Kornfeld O, Jesudason R, Foo C, Höckendorf B, Corrada Bravo H, Town JP, Wei R, Rios A, Chandrasekar V, Heinlein M, Chuong AS, Cai S, Lu CS, Coelho P, Mis M, Celen C, Kljavin N, Jiang J, Richmond D, Thakore P, Benito-Gutiérrez E, Geiger-Schuller K, Hleap JS, Kayagaki N, de Sousa E Melo F, McGinnis L, Li B, Singh A, Garraway L, Rozenblatt-Rosen O, Regev A, Lubeck E. Kudo T, et al. Among authors: regev a. Nat Biotechnol. 2024 Oct 7. doi: 10.1038/s41587-024-02391-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 39375449
Massively parallel single-nucleus RNA-seq with DroNc-seq.
Habib N, Avraham-Davidi I, Basu A, Burks T, Shekhar K, Hofree M, Choudhury SR, Aguet F, Gelfand E, Ardlie K, Weitz DA, Rozenblatt-Rosen O, Zhang F, Regev A. Habib N, et al. Among authors: regev a. Nat Methods. 2017 Oct;14(10):955-958. doi: 10.1038/nmeth.4407. Epub 2017 Aug 28. Nat Methods. 2017. PMID: 28846088 Free PMC article.
The Human Cell Atlas: from vision to reality.
Rozenblatt-Rosen O, Stubbington MJT, Regev A, Teichmann SA. Rozenblatt-Rosen O, et al. Among authors: regev a. Nature. 2017 Oct 18;550(7677):451-453. doi: 10.1038/550451a. Nature. 2017. PMID: 29072289 No abstract available.
Nuclei multiplexing with barcoded antibodies for single-nucleus genomics.
Gaublomme JT, Li B, McCabe C, Knecht A, Yang Y, Drokhlyansky E, Van Wittenberghe N, Waldman J, Dionne D, Nguyen L, De Jager PL, Yeung B, Zhao X, Habib N, Rozenblatt-Rosen O, Regev A. Gaublomme JT, et al. Among authors: regev a. Nat Commun. 2019 Jul 2;10(1):2907. doi: 10.1038/s41467-019-10756-2. Nat Commun. 2019. PMID: 31266958 Free PMC article.
High-definition spatial transcriptomics for in situ tissue profiling.
Vickovic S, Eraslan G, Salmén F, Klughammer J, Stenbeck L, Schapiro D, Äijö T, Bonneau R, Bergenstråhle L, Navarro JF, Gould J, Griffin GK, Borg Å, Ronaghi M, Frisén J, Lundeberg J, Regev A, Ståhl PL. Vickovic S, et al. Among authors: regev a. Nat Methods. 2019 Oct;16(10):987-990. doi: 10.1038/s41592-019-0548-y. Epub 2019 Sep 9. Nat Methods. 2019. PMID: 31501547 Free PMC article.
A single-cell landscape of high-grade serous ovarian cancer.
Izar B, Tirosh I, Stover EH, Wakiro I, Cuoco MS, Alter I, Rodman C, Leeson R, Su MJ, Shah P, Iwanicki M, Walker SR, Kanodia A, Melms JC, Mei S, Lin JR, Porter CBM, Slyper M, Waldman J, Jerby-Arnon L, Ashenberg O, Brinker TJ, Mills C, Rogava M, Vigneau S, Sorger PK, Garraway LA, Konstantinopoulos PA, Liu JF, Matulonis U, Johnson BE, Rozenblatt-Rosen O, Rotem A, Regev A. Izar B, et al. Among authors: regev a. Nat Med. 2020 Aug;26(8):1271-1279. doi: 10.1038/s41591-020-0926-0. Epub 2020 Jun 22. Nat Med. 2020. PMID: 32572264 Free PMC article.
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.
McFarland JM, Paolella BR, Warren A, Geiger-Schuller K, Shibue T, Rothberg M, Kuksenko O, Colgan WN, Jones A, Chambers E, Dionne D, Bender S, Wolpin BM, Ghandi M, Tirosh I, Rozenblatt-Rosen O, Roth JA, Golub TR, Regev A, Aguirre AJ, Vazquez F, Tsherniak A. McFarland JM, et al. Among authors: regev a. Nat Commun. 2020 Aug 27;11(1):4296. doi: 10.1038/s41467-020-17440-w. Nat Commun. 2020. PMID: 32855387 Free PMC article.
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity.
Kinker GS, Greenwald AC, Tal R, Orlova Z, Cuoco MS, McFarland JM, Warren A, Rodman C, Roth JA, Bender SA, Kumar B, Rocco JW, Fernandes PACM, Mader CC, Keren-Shaul H, Plotnikov A, Barr H, Tsherniak A, Rozenblatt-Rosen O, Krizhanovsky V, Puram SV, Regev A, Tirosh I. Kinker GS, et al. Among authors: regev a. Nat Genet. 2020 Nov;52(11):1208-1218. doi: 10.1038/s41588-020-00726-6. Epub 2020 Oct 30. Nat Genet. 2020. PMID: 33128048 Free PMC article.
An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.
Zhang H, Madi A, Yosef N, Chihara N, Awasthi A, Pot C, Lambden C, Srivastava A, Burkett PR, Nyman J, Christian E, Etminan Y, Lee A, Stroh H, Xia J, Karwacz K, Thakore PI, Acharya N, Schnell A, Wang C, Apetoh L, Rozenblatt-Rosen O, Anderson AC, Regev A, Kuchroo VK. Zhang H, et al. Among authors: regev a. Cell Rep. 2020 Nov 24;33(8):108433. doi: 10.1016/j.celrep.2020.108433. Cell Rep. 2020. PMID: 33238123 Free PMC article.
630 results