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3,538 results

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A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
Kohsaka S, Yagishita S, Shirai Y, Matsuno Y, Ueno T, Kojima S, Ikeuchi H, Ikegami M, Kitada R, Yoshioka KI, Toshimitsu K, Tabata K, Yokoi A, Doi T, Yamamoto N, Owa T, Hamada A, Mano H. Kohsaka S, et al. Among authors: ueno t. NPJ Precis Oncol. 2024 May 24;8(1):117. doi: 10.1038/s41698-024-00610-0. NPJ Precis Oncol. 2024. PMID: 38789724 Free PMC article.
MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.
Ikegami M, Kohsaka S, Hirose T, Ueno T, Inoue S, Kanomata N, Yamauchi H, Mori T, Sekine S, Inamoto Y, Yatabe Y, Kobayashi H, Tanaka S, Mano H. Ikegami M, et al. Among authors: ueno t. Commun Biol. 2021 Dec 15;4(1):1396. doi: 10.1038/s42003-021-02930-4. Commun Biol. 2021. PMID: 34912045 Free PMC article.
Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling.
Kohsaka S, Tada Y, Ando M, Nakaguro M, Shirai Y, Ueno T, Kojima S, Hirai H, Saigusa N, Kano S, Tsukahara K, Togashi T, Ozawa H, Kondo T, Okami K, Takahashi H, Kawakita D, Fushimi C, Suzuki T, Shimizu A, Okamoto I, Okada T, Sato Y, Imanishi Y, Watanabe Y, Sakai A, Ebisumoto K, Sato Y, Urano M, Honma Y, Yamazaki K, Ueki Y, Hanazawa T, Saito Y, Shimura T, Nagao T, Mano H. Kohsaka S, et al. Among authors: ueno t. NPJ Precis Oncol. 2022 Nov 4;6(1):82. doi: 10.1038/s41698-022-00324-1. NPJ Precis Oncol. 2022. PMID: 36333410 Free PMC article.
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway.
Ikeuchi H, Matsuno Y, Kusumoto-Matsuo R, Kojima S, Ueno T, Ikegami M, Kitada R, Sumiyoshi-Okuma H, Kojima Y, Yonemori K, Yatabe Y, Takamochi K, Suzuki K, Yoshioka KI, Mano H, Kohsaka S. Ikeuchi H, et al. Among authors: ueno t. Oncogene. 2024 Oct;43(41):3037-3048. doi: 10.1038/s41388-024-03105-1. Epub 2024 Aug 3. Oncogene. 2024. PMID: 39095584
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.
Mizuno S, Ikegami M, Koyama T, Sunami K, Ogata D, Kage H, Yanagaki M, Ikeuchi H, Ueno T, Tanikawa M, Oda K, Osuga Y, Mano H, Kohsaka S. Mizuno S, et al. Among authors: ueno t. Mol Cancer Ther. 2023 Feb 1;22(2):227-239. doi: 10.1158/1535-7163.MCT-22-0302. Mol Cancer Ther. 2023. PMID: 36442478 Free PMC article.
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers.
Kobayashi Y, Niida A, Nagayama S, Saeki K, Haeno H, Takahashi KK, Hayashi S, Ozato Y, Saito H, Hasegawa T, Nakamura H, Tobo T, Kitagawa A, Sato K, Shimizu D, Hirata H, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K. Kobayashi Y, et al. Among authors: ueno t. Br J Cancer. 2023 Oct;129(7):1105-1118. doi: 10.1038/s41416-023-02395-8. Epub 2023 Aug 18. Br J Cancer. 2023. PMID: 37596408 Free PMC article.
Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation.
Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K. Hayakawa D, et al. Among authors: ueno t. Thorac Cancer. 2020 Jan;11(1):140-149. doi: 10.1111/1759-7714.13255. Epub 2019 Nov 22. Thorac Cancer. 2020. PMID: 31758670 Free PMC article.
3,538 results