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Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates.
Córdoba KM, Jericó D, Jiang L, Collantes M, Alegre M, García-Ruiz L, Manzanilla O, Sampedro A, Herranz JM, Insausti I, Martinez de la Cuesta A, Urigo F, Alcaide P, Morán M, Martín MA, Lanciego JL, Lefebvre T, Gouya L, Quincoces G, Unzu C, Hervas-Stubbs S, Falcón-Pérez JM, Alegre E, Aldaz A, Fernández-Seara MA, Peñuelas I, Berraondo P, Martini PGV, Avila MA, Fontanellas A. Córdoba KM, et al. Among authors: alegre e. Gut. 2025 Jan 17;74(2):270-283. doi: 10.1136/gutjnl-2024-332619. Gut. 2025. PMID: 39366725 Free article.
MAPK inhibitors dynamically affect melanoma release of immune NKG2D-ligands, as soluble protein and extracellular vesicle-associated.
López-Borrego S, Campos-Silva C, Sandúa A, Camino T, Téllez-Pérez L, Alegre E, Beneitez A, Jara-Acevedo R, Paschen A, Pardo M, González Á, Valés-Gómez M. López-Borrego S, et al. Among authors: alegre e. Front Cell Dev Biol. 2023 Jan 16;10:1055288. doi: 10.3389/fcell.2022.1055288. eCollection 2022. Front Cell Dev Biol. 2023. PMID: 36726591 Free PMC article.
mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks.
Jericó D, Córdoba KM, Jiang L, Schmitt C, Morán M, Sampedro A, Alegre M, Collantes M, Santamaría E, Alegre E, Culerier C, de Mendoza AE, Oyarzabal J, Martín MA, Peñuelas I, Ávila MA, Gouya L, Martini PGV, Fontanellas A. Jericó D, et al. Among authors: alegre m, alegre e. Mol Ther Nucleic Acids. 2021 May 19;25:207-219. doi: 10.1016/j.omtn.2021.05.010. eCollection 2021 Sep 3. Mol Ther Nucleic Acids. 2021. PMID: 34458006 Free PMC article.
Trastuzumab and thyroid dysfunction: An association to be aware of.
Sánchez-Bayona R, Garcia Del Barrio MA, Alegre E, Fernandez-Hidalgo OA, Eslava MS. Sánchez-Bayona R, et al. Among authors: alegre e. J Cancer Res Ther. 2022 Jul-Sep;18(4):1183-1185. doi: 10.4103/jcrt.JCRT_66_19. J Cancer Res Ther. 2022. PMID: 36149184 Free article.
PSA reactivity in extracellular microvesicles to commercial immunoassays.
Sandúa A, Sanmamed MF, Rodríguez M, Ancizu-Marckert J, Gúrpide A, Perez-Gracia JL, Alegre E, González Á. Sandúa A, et al. Among authors: alegre e. Clin Chim Acta. 2023 Mar 15;543:117303. doi: 10.1016/j.cca.2023.117303. Epub 2023 Mar 21. Clin Chim Acta. 2023. PMID: 36948237 Free article.
77 results