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In vitro and in vivo characterization of the JAK1 selectivity of upadacitinib (ABT-494).
Parmentier JM, Voss J, Graff C, Schwartz A, Argiriadi M, Friedman M, Camp HS, Padley RJ, George JS, Hyland D, Rosebraugh M, Wishart N, Olson L, Long AJ. Parmentier JM, et al. Among authors: long aj. BMC Rheumatol. 2018 Aug 28;2:23. doi: 10.1186/s41927-018-0031-x. eCollection 2018. BMC Rheumatol. 2018. PMID: 30886973 Free PMC article.
The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.
Ge T, Jhala G, Fynch S, Akazawa S, Litwak S, Pappas EG, Catterall T, Vakil I, Long AJ, Olson LM, Krishnamurthy B, Kay TW, Thomas HE. Ge T, et al. Among authors: long aj. Front Immunol. 2020 Dec 4;11:588543. doi: 10.3389/fimmu.2020.588543. eCollection 2020. Front Immunol. 2020. PMID: 33343569 Free PMC article.
Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas.
Long AJ, Sampson E, McCarthy RW, Harris CM, Barnard M, Shi D, Conlon D, Caldwell R, Honor D, Wishart N, Hoemann M, Duggan L, Fritz D, Stedman C, O'Connor E, Mikaelian I, Schwartz A. Long AJ, et al. Toxicol Pathol. 2016 Oct;44(7):998-1012. doi: 10.1177/0192623316654015. Epub 2016 Jun 19. Toxicol Pathol. 2016. PMID: 27324990
Pharmacokinetics, Efficacy, and Safety of a SARS-CoV-2 Antibody Treatment in Pediatric Participants: An Open-Label Addendum of a Placebo-Controlled, Randomized Phase 2/3 Trial.
Upadhyaya HP, Chien JY, Long AJ, Bohm MS, Kallewaard NL, Macpherson LF, Patel DR, Hufford MM, Krull CJ, Ang JY, Chen P, Muller WJ, Potts JA, Quinn T, Williams M; BLAZE-1 Investigators. Upadhyaya HP, et al. Among authors: long aj. Infect Dis Ther. 2023 Jul;12(7):1861-1873. doi: 10.1007/s40121-023-00832-y. Epub 2023 Jun 17. Infect Dis Ther. 2023. PMID: 37329415 Free PMC article.
53 results