Ito N - Search Results

1

Intron retention as an excellent marker for diagnosing depression and for discovering new potential pathways for drug intervention.

Okada N, Oshima K, Maruko A, Sekine M, Ito N, Wakasugi A, Mori E, Odaguchi H, Kobayashi Y. Okada N, et al. Among authors: ito n. Front Psychiatry. 2024 Sep 19;15:1450708. doi: 10.3389/fpsyt.2024.1450708. eCollection 2024. Front Psychiatry. 2024. PMID: 39364384 Free PMC article.

2

Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice.

Ito N, Hirose E, Ishida T, Hori A, Nagai T, Kobayashi Y, Kiyohara H, Oikawa T, Hanawa T, Odaguchi H. Ito N, et al. J Neuroinflammation. 2017 May 3;14(1):98. doi: 10.1186/s12974-017-0876-8. J Neuroinflammation. 2017. PMID: 28468634 Free PMC article.

3

Emotional Impairments and Neuroinflammation are Induced in Male Mice Invulnerable to Repeated Social Defeat Stress.

Ito N, Sasaki K, Takemoto H, Kobayashi Y, Isoda H, Odaguchi H. Ito N, et al. Neuroscience. 2020 Sep 1;443:148-163. doi: 10.1016/j.neuroscience.2020.07.023. Epub 2020 Jul 22. Neuroscience. 2020. PMID: 32707290

4

Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice.

Ito N, Takemoto H, Hasegawa A, Sugiyama C, Honma K, Nagai T, Kobayashi Y, Odaguchi H. Ito N, et al. Exp Gerontol. 2020 Dec;142:111109. doi: 10.1016/j.exger.2020.111109. Epub 2020 Oct 16. Exp Gerontol. 2020. PMID: 33069781

5

Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress.

Ito N, Sasaki K, Hirose E, Nagai T, Isoda H, Odaguchi H. Ito N, et al. Gene. 2022 Jan 5;806:145920. doi: 10.1016/j.gene.2021.145920. Epub 2021 Aug 26. Gene. 2022. PMID: 34455026

6

Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice.

Ito N, Maruko A, Oshima K, Yoshida M, Honma K, Sugiyama C, Nagai T, Kobayashi Y, Odaguchi H, Okada N. Ito N, et al. Aging (Albany NY). 2022 Jan 3;14(1):109-142. doi: 10.18632/aging.203811. Epub 2022 Jan 3. Aging (Albany NY). 2022. PMID: 34979499 Free PMC article.

7

Intron retention is a stress response in sensor genes and is restored by Japanese herbal medicines: A basis for future clinical applications.

Vu TD, Ito N, Oshima K, Maruko A, Nishi A, Mizoguchi K, Odaguchi H, Kobayashi Y, Okada N. Vu TD, et al. Among authors: ito n. Gene. 2022 Jul 1;830:146496. doi: 10.1016/j.gene.2022.146496. Epub 2022 May 2. Gene. 2022. PMID: 35504437 Free article.

8

Nobiletin-rich kososan, a Kampo formula, prevents the onset of apathy-like behavior and neuroinflammation in sickness behavior mouse model induced by increasing doses of lipopolysaccharide.

Ito N, Miki R, Kawada N, Yoshida M, Kobayashi Y. Ito N, et al. Neuroscience. 2025 Jan 26;565:342-357. doi: 10.1016/j.neuroscience.2024.11.072. Epub 2024 Dec 5. Neuroscience. 2025. PMID: 39645074 Free article.

9

A possible mechanism underlying an antidepressive-like effect of Kososan, a Kampo medicine, via the hypothalamic orexinergic system in the stress-induced depression-like model mice.

Ito N, Yabe T, Nagai T, Oikawa T, Yamada H, Hanawa T. Ito N, et al. Biol Pharm Bull. 2009 Oct;32(10):1716-22. doi: 10.1248/bpb.32.1716. Biol Pharm Bull. 2009. PMID: 19801833 Free article.

10

I.c.v. administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation.

Ito N, Yabe T, Gamo Y, Nagai T, Oikawa T, Yamada H, Hanawa T. Ito N, et al. Neuroscience. 2008 Dec 10;157(4):720-32. doi: 10.1016/j.neuroscience.2008.09.042. Epub 2008 Oct 1. Neuroscience. 2008. PMID: 18952152

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