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Page 1
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Marcus K, Huang Y, Subramanian S, Gee CL, Gorday K, Ghaffari-Kashani S, Luo XR, Zheng L, O'Donnell M, Subramaniam S, Kuriyan J. Marcus K, et al. Among authors: gee cl. Nat Struct Mol Biol. 2024 Mar;31(3):424-435. doi: 10.1038/s41594-023-01177-3. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177685 Free PMC article.
Structural basis for dimerization quality control.
Mena EL, Jevtić P, Greber BJ, Gee CL, Lew BG, Akopian D, Nogales E, Kuriyan J, Rape M. Mena EL, et al. Among authors: gee cl. Nature. 2020 Oct;586(7829):452-456. doi: 10.1038/s41586-020-2636-7. Epub 2020 Aug 19. Nature. 2020. PMID: 32814905 Free PMC article.
Structural basis and regulation of the reductive stress response.
Manford AG, Mena EL, Shih KY, Gee CL, McMinimy R, Martínez-González B, Sherriff R, Lew B, Zoltek M, Rodríguez-Pérez F, Woldesenbet M, Kuriyan J, Rape M. Manford AG, et al. Among authors: gee cl. Cell. 2021 Oct 14;184(21):5375-5390.e16. doi: 10.1016/j.cell.2021.09.002. Epub 2021 Sep 24. Cell. 2021. PMID: 34562363 Free PMC article.
Deconstruction of the Ras switching cycle through saturation mutagenesis.
Bandaru P, Shah NH, Bhattacharyya M, Barton JP, Kondo Y, Cofsky JC, Gee CL, Chakraborty AK, Kortemme T, Ranganathan R, Kuriyan J. Bandaru P, et al. Among authors: gee cl. Elife. 2017 Jul 7;6:e27810. doi: 10.7554/eLife.27810. Elife. 2017. PMID: 28686159 Free PMC article.
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria.
Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. Gee CL, et al. Sci Signal. 2012 Jan 24;5(208):ra7. doi: 10.1126/scisignal.2002525. Sci Signal. 2012. PMID: 22275220 Free PMC article.
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.
Narayanan D, Larsen ASG, Gauger SJ, Adafia R, Hammershøi RB, Hamborg L, Bruus-Jensen J, Griem-Krey N, Gee CL, Frølund B, Stratton MM, Kuriyan J, Kastrup JS, Langkilde AE, Wellendorph P, Solbak SMØ. Narayanan D, et al. Among authors: gee cl. Protein Sci. 2024 Oct;33(10):e5152. doi: 10.1002/pro.5152. Protein Sci. 2024. PMID: 39275999 Free PMC article.
53 results