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Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice.
Verma SK, Ana-Sosa-Batiz F, Timis J, Shafee N, Maule E, Pinto PBA, Conner C, Valentine KM, Cowley DO, Miller R, Elong Ngono A, Tran L, Varghese K, Dos Santos Alves RP, Hastie KM, Saphire EO, Webb DR, Jarnagin K, Kim K, Shresta S. Verma SK, et al. Among authors: saphire eo. EBioMedicine. 2024 Oct;108:105361. doi: 10.1016/j.ebiom.2024.105361. Epub 2024 Sep 30. EBioMedicine. 2024. PMID: 39353281 Free PMC article.
Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation.
Olmedillas E, Rajamanickam RR, Avalos RD, Sosa FA, Zandonatti MA, Harkins SS, Shresta S, Hastie KM, Saphire EO. Olmedillas E, et al. Among authors: saphire eo. bioRxiv [Preprint]. 2023 Dec 15:2023.12.14.571764. doi: 10.1101/2023.12.14.571764. bioRxiv. 2023. PMID: 38168261 Free PMC article. Preprint.
Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers.
Moreno LB, de Albuquerque JB, Neary JM, Nguyen T, Hastie KM, Landeras-Bueno S, Hariharan C, Nathan A, Getz MA, Gayton AC, Khatri A, Gaiha GD, Saphire EO, Luster AD, Moon JJ. Moreno LB, et al. Among authors: saphire eo. bioRxiv [Preprint]. 2023 Nov 17:2023.11.16.566918. doi: 10.1101/2023.11.16.566918. bioRxiv. 2023. Update in: Front Immunol. 2024 Mar 11;15:1329846. doi: 10.3389/fimmu.2024.1329846 PMID: 38014059 Free PMC article. Updated. Preprint.
A broadly-neutralizing antibody against Ebolavirus glycoprotein that potentiates the breadth and neutralization potency of other antibodies.
Donnellan FR, Rayaprolu V, Rijal P, O'Dowd V, Parvate A, Callaway H, Hariharan C, Parekh D, Hui S, Shaffer K, Avalos RD, Hastie K, Schimanski L, Müller-Kräuter H, Strecker T, Balaram A, Halfmann P, Saphire EO, Lightwood DJ, Townsend AR, Draper SJ. Donnellan FR, et al. Among authors: saphire eo. bioRxiv [Preprint]. 2024 Jun 25:2024.06.21.600001. doi: 10.1101/2024.06.21.600001. bioRxiv. 2024. PMID: 38979279 Free PMC article. Preprint.
Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles.
Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, Saphire EO, Krammer F, Lauffenburger DA, Barouch DH, Alter G. Kaplonek P, et al. Among authors: saphire eo. bioRxiv [Preprint]. 2021 Aug 31:2021.08.31.458247. doi: 10.1101/2021.08.31.458247. bioRxiv. 2021. Update in: Sci Transl Med. 2022 May 18;14(645):eabm2311. doi: 10.1126/scitranslmed.abm2311 PMID: 34494026 Free PMC article. Updated. Preprint.
Co-immunization with spike and nucleocapsid based DNA vaccines for long-term protective immunity against SARS-CoV-2 Omicron.
Pinto PBA, Timis J, Chuensirikulchai K, Li QH, Lu HH, Maule E, Nguyen M, Alves RPDS, Verma SK, Ana-Sosa-Batiz F, Valentine K, Landeras-Bueno S, Kim K, Hastie K, Saphire EO, Alves A, Elong Ngono A, Shresta S. Pinto PBA, et al. Among authors: saphire eo. NPJ Vaccines. 2024 Dec 19;9(1):252. doi: 10.1038/s41541-024-01043-3. NPJ Vaccines. 2024. PMID: 39702529 Free PMC article.
Author Correction: Immunological memory diversity in the human upper airway.
Ramirez SI, Faraji F, Hills LB, Lopez PG, Goodwin B, Stacey HD, Sutton HJ, Hastie KM, Saphire EO, Kim HJ, Mashoof S, Yan CH, DeConde AS, Levi G, Crotty S. Ramirez SI, et al. Among authors: saphire eo. Nature. 2024 Dec 16. doi: 10.1038/s41586-024-08519-1. Online ahead of print. Nature. 2024. PMID: 39681658 No abstract available.
A noncanonical glycoprotein H complex enhances cytomegalovirus entry.
Norris MJ, Henderson LA, Siddiquey MNA, Yin J, Yoo K, Brunel S, Saphire EO, Benedict CA, Kamil JP. Norris MJ, et al. Among authors: saphire eo. bioRxiv [Preprint]. 2024 Oct 13:2024.10.13.617647. doi: 10.1101/2024.10.13.617647. bioRxiv. 2024. PMID: 39416215 Free PMC article. Preprint.
191 results