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Trametinib in combination with hydroxychloroquine or palbociclib in advanced metastatic pancreatic cancer: data from a retrospective, multicentric cohort (AIO AIO-TF/PAK-0123).
Witte D, Pretzell I, Reissig TM, Stein A, Velthaus JL, Alig A, Bohnenberger H, Knödler M, Kurreck A, Sulzer S, Beyer G, Dorman K, Fröhlich T, Hegenberg S, Lugnier C, Saborowski A, Vogel A, Lange S, Reichert M, Flade F, Klaas L, Utpatel K, Becker H, Bleckmann A, Wethmar K, Reinacher-Schick A, Westphalen CB. Witte D, et al. Among authors: lange s. J Cancer Res Clin Oncol. 2024 Oct 1;150(10):438. doi: 10.1007/s00432-024-05954-5. J Cancer Res Clin Oncol. 2024. PMID: 39352477 Free PMC article.
Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems.
Peschke K, Jakubowsky H, Schäfer A, Maurer C, Lange S, Orben F, Bernad R, Harder FN, Eiber M, Öllinger R, Steiger K, Schlitter M, Weichert W, Mayr U, Phillip V, Schlag C, Schmid RM, Braren RF, Kong B, Demir IE, Friess H, Rad R, Saur D, Schneider G, Reichert M. Peschke K, et al. Among authors: lange s. EMBO Mol Med. 2022 Apr 7;14(4):e14876. doi: 10.15252/emmm.202114876. Epub 2022 Feb 4. EMBO Mol Med. 2022. PMID: 35119792 Free PMC article.
Early clinical trial unit tumor board: a real-world experience in a national cancer network.
Weiss L, Dorman K, Boukovala M, Schwinghammer F, Jordan P, Fey T, Hasselmann K, Subklewe M, Bücklein V, Bargou R, Goebeler M, Sayehli C, Spoerl S, Lüke F, Heudobler D, Claus R, von Luettichau I, Lorenzen S, Lange S, Westphalen CB, von Bergwelt-Baildon M, Heinemann V, Gießen-Jung C. Weiss L, et al. Among authors: lange s. J Cancer Res Clin Oncol. 2023 Nov;149(14):13383-13390. doi: 10.1007/s00432-023-05196-x. Epub 2023 Jul 25. J Cancer Res Clin Oncol. 2023. PMID: 37490102 Free PMC article.
Implementing cell-free DNA of pancreatic cancer patient-derived organoids for personalized oncology.
Dantes Z, Yen HY, Pfarr N, Winter C, Steiger K, Muckenhuber A, Hennig A, Lange S, Engleitner T, Öllinger R, Maresch R, Orben F, Heid I, Kaissis G, Shi K, Topping G, Stögbauer F, Wirth M, Peschke K, Papargyriou A, Rezaee-Oghazi M, Feldmann K, Schäfer AP, Ranjan R, Lubeseder-Martellato C, Stange DE, Welsch T, Martignoni M, Ceyhan GO, Friess H, Herner A, Liotta L, Treiber M, von Figura G, Abdelhafez M, Klare P, Schlag C, Algül H, Siveke J, Braren R, Weirich G, Weichert W, Saur D, Rad R, Schmid RM, Schneider G, Reichert M. Dantes Z, et al. Among authors: lange s. JCI Insight. 2020 Aug 6;5(15):e137809. doi: 10.1172/jci.insight.137809. JCI Insight. 2020. PMID: 32614802 Free PMC article.
PALLD mutation in a European family conveys a stromal predisposition for familial pancreatic cancer.
Liotta L, Lange S, Maurer HC, Olive KP, Braren R, Pfarr N, Burger S, Muckenhuber A, Jesinghaus M, Steiger K, Weichert W, Friess H, Schmid R, Algül H, Jost PJ, Ramser J, Fischer C, Quante AS, Reichert M, Quante M. Liotta L, et al. Among authors: lange s. JCI Insight. 2021 Mar 25;6(8):e141532. doi: 10.1172/jci.insight.141532. JCI Insight. 2021. PMID: 33764904 Free PMC article.
Post-neoadjuvant assessment of tumour budding according to ITBCC subgroups delivers stage- and regression-grade independent prognostic information in intestinal-type gastric adenocarcinoma.
Jesinghaus M, Herz AL, Kohlruss M, Silva M, Grass A, Lange S, Novotny A, Ott K, Schmidt T, Gaida M, Hapfelmeier A, Denkert C, Weichert W, Keller G. Jesinghaus M, et al. Among authors: lange s. J Pathol Clin Res. 2022 Sep;8(5):448-457. doi: 10.1002/cjp2.284. Epub 2022 Jun 17. J Pathol Clin Res. 2022. PMID: 35715937 Free PMC article.
pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification.
Foersch S, Lang-Schwarz C, Eckstein M, Geppert C, Schmitt M, Konukiewitz B, Groll T, Schicktanz F, Engel J, Gleitsmann M, Westhoff CC, Frickel N, Litmeyer AS, Grass A, Jank P, Lange S, Tschurtschenthaler M, Wilhelm D, Roth W, Vieth M, Denkert C, Nagtegaal I, Weichert W, Jesinghaus M. Foersch S, et al. Among authors: lange s. Br J Cancer. 2022 Oct;127(7):1270-1278. doi: 10.1038/s41416-022-01889-1. Epub 2022 Jul 21. Br J Cancer. 2022. PMID: 35864156 Free PMC article.
Post-neoadjuvant cellular dissociation grading based on tumour budding and cell nest size is associated with therapy response and survival in oesophageal squamous cell carcinoma.
Jesinghaus M, Boxberg M, Wilhelm D, Münch S, Dapper H, Quante M, Schlag C, Lange S, Budczies J, Konukiewitz B, Mollenhauer M, Schlitter AM, Becker KF, Feith M, Friess H, Steiger K, Combs SE, Weichert W. Jesinghaus M, et al. Among authors: lange s. Br J Cancer. 2019 Dec;121(12):1050-1057. doi: 10.1038/s41416-019-0623-2. Epub 2019 Nov 6. Br J Cancer. 2019. PMID: 31690830 Free PMC article.
Expert-Guided Large Language Models for Clinical Decision Support in Precision Oncology.
Lammert J, Dreyer T, Mathes S, Kuligin L, Borm KJ, Schatz UA, Kiechle M, Lörsch AM, Jung J, Lange S, Pfarr N, Durner A, Schwamborn K, Winter C, Ferber D, Kather JN, Mogler C, Illert AL, Tschochohei M. Lammert J, et al. Among authors: lange s. JCO Precis Oncol. 2024 Oct;8:e2400478. doi: 10.1200/PO-24-00478. Epub 2024 Oct 30. JCO Precis Oncol. 2024. PMID: 39475661
1,499 results