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Clinical Meaningfulness in Alzheimer's Disease Clinical Trials. A Report from the EU-US CTAD Task Force.
Angioni D, Cummings J, Lansdall CJ, Middleton L, Sampaio C, Gauthier S, Cohen S, Petersen RC, Rentz DM, Wessels AM, Hendrix SB, Jessen F, Carrillo MC, Doody RS, Irizarry M, Andrews JS, Vellas B, Aisen P. Angioni D, et al. Among authors: gauthier s. J Prev Alzheimers Dis. 2024;11(5):1219-1227. doi: 10.14283/jpad.2024.112. J Prev Alzheimers Dis. 2024. PMID: 39350367 Free PMC article.
Clinical Correlates of the PET-based Braak Staging Framework in Alzheimer's Disease.
Macedo AC, Durço DFPA, Tissot C, Therriault J, Vilela de Faria AO, Aumont É, Servaes S, Rahmouni N, Fernandez-Arias J, Wang YT, Lussier FZ, Bieger A, Zimmer ER, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: gauthier s. J Prev Alzheimers Dis. 2024;11(2):414-421. doi: 10.14283/jpad.2024.15. J Prev Alzheimers Dis. 2024. PMID: 38374747 Review.
Biomarker-based staging of Alzheimer disease: rationale and clinical applications.
Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, Zetterberg H, Bateman RJ, Scheltens P, Blennow K, Sperling R, Hansson O, Jack CR Jr, Rosa-Neto P. Therriault J, et al. Among authors: gauthier s. Nat Rev Neurol. 2024 Apr;20(4):232-244. doi: 10.1038/s41582-024-00942-2. Epub 2024 Mar 1. Nat Rev Neurol. 2024. PMID: 38429551 Review.
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network–Trials Unit. Wagemann O, et al. Among authors: gauthier s. JAMA Neurol. 2024 Jun 1;81(6):582-593. doi: 10.1001/jamaneurol.2024.0991. JAMA Neurol. 2024. PMID: 38683602 Free PMC article. Clinical Trial.
Decentralized clinical trials for medications to reduce the risk of dementia: Consensus report and guidance.
Howard L, Abdelnour C, Abner EL, Allegri RF, Dodge HH, Gauthier S, Hoyos CM, Jicha GA, Kehoe PG, Mummery CJ, Ogunniyi A, Scarmeas N, Chen X, Titiner JR, Weber CR; Clinical Trial Methodology Working review group members; Peters R. Howard L, et al. Among authors: gauthier s. Alzheimers Dement. 2024 Jul;20(7):4625-4634. doi: 10.1002/alz.13891. Epub 2024 Jun 2. Alzheimers Dement. 2024. PMID: 38824659 Free PMC article.
Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer's disease pathology.
Therriault J, Woo MS, Salvadó G, Gobom J, Karikari TK, Janelidze S, Servaes S, Rahmouni N, Tissot C, Ashton NJ, Benedet AL, Montoliu-Gaya L, Macedo AC, Lussier FZ, Stevenson J, Vitali P, Friese MA, Massarweh G, Soucy JP, Pascoal TA, Stomrud E, Palmqvist S, Mattsson-Carlgren N, Gauthier S, Zetterberg H, Hansson O, Blennow K, Rosa-Neto P. Therriault J, et al. Among authors: gauthier s. Mol Neurodegener. 2024 Jan 7;19(1):2. doi: 10.1186/s13024-023-00689-2. Mol Neurodegener. 2024. PMID: 38185677 Free PMC article.
Neurobehavioral Mechanisms Influencing the Association Between Generativity, the Desire to Promote Well-Being of Younger Generations, and Purpose in Life in Older Adults at Risk for Alzheimer's Disease.
Walker CS, Li L, Baracchini G, Tremblay-Mercier J, Spreng RN; PREVENT-AD Research Group; Geddes MR. Walker CS, et al. J Gerontol B Psychol Sci Soc Sci. 2024 Jun 1;79(6):gbae060. doi: 10.1093/geronb/gbae060. J Gerontol B Psychol Sci Soc Sci. 2024. PMID: 38623965 Free PMC article.
Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females -evidence from two independent cohorts.
Wang YT, Therriault J, Tissot C, Servaes S, Rahmouni N, Macedo AC, Fernandez-Arias J, Mathotaarachchi SS, Stevenson J, Lussier FZ, Benedet AL, Pascoal TA, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P. Wang YT, et al. Among authors: gauthier s. Alzheimers Res Ther. 2024 Jul 22;16(1):162. doi: 10.1186/s13195-024-01509-5. Alzheimers Res Ther. 2024. PMID: 39034389 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 39112086
1,135 results