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Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer.
Wang J, Xiu J, Battaglin F, Arai H, Soni S, Zhang W, Goldberg RM, Philip PA, Seeber A, Hwang JJ, Shields AF, Marshall JL, Astaturov I, Liu T, Lockhart AC, Korn WM, Shen L, Lenz HJ. Wang J, et al. Among authors: shen l. NPJ Precis Oncol. 2024 Sep 30;8(1):214. doi: 10.1038/s41698-024-00694-8. NPJ Precis Oncol. 2024. PMID: 39349771 Free PMC article.
Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS-MAPK pathway and TP53 as potential predictors of immunotherapy efficacy.
Wang JY, Xiu J, Baca Y, Arai H, Battaglin F, Kawanishi N, Soni S, Zhang W, Millstein J, Shields AF, Grothey A, Weinberg BA, Marshall JL, Lou E, Khushman M, Sohal DPS, Hall MJ, Oberley M, Spetzler D, Shen L, Korn WM, Lenz HJ. Wang JY, et al. Among authors: shen l. Ann Oncol. 2021 Jul;32(7):906-916. doi: 10.1016/j.annonc.2021.03.203. Epub 2021 Mar 30. Ann Oncol. 2021. PMID: 33798656 Free article.
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
Wang J, Xiu J, Farrell A, Baca Y, Arai H, Battaglin F, Kawanishi N, Soni S, Zhang W, Millstein J, Shields AF, Grothey A, Weinberg BA, Marshall JL, Lou E, Khushman M, Sohal DPS, Hall MJ, Liu T, Oberley M, Spetzler D, Korn WM, Shen L, Lenz HJ. Wang J, et al. Among authors: shen l. Lancet Oncol. 2023 Feb;24(2):151-161. doi: 10.1016/S1470-2045(22)00783-5. Epub 2023 Jan 18. Lancet Oncol. 2023. PMID: 36681091 Free PMC article.
Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation.
Cui X, Dong Y, Zhan Q, Huang Y, Zhu Q, Zhang Z, Yang G, Wang L, Shen S, Zhao J, Lin Z, Sun J, Su Z, Xiao Y, Zhang C, Liang Y, Shen L, Ji L, Zhang X, Yin J, Wang H, Chen Z, Ju Z, Jiang C, Le R, Gao S. Cui X, et al. Among authors: shen l. Sci China Life Sci. 2024 Dec 27. doi: 10.1007/s11427-024-2754-9. Online ahead of print. Sci China Life Sci. 2024. PMID: 39754007
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