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Replacement of nitro function by free boronic acid in non-steroidal anti-androgens.
Šlechta P, Viták R, Bárta P, Koucká K, Berková M, Žďárová D, Petríková A, Kuneš J, Kubíček V, Doležal M, Kučera R, Kučerová-Chlupáčová M. Šlechta P, et al. Among authors: koucka k. RSC Med Chem. 2024 Sep 10;15(12):4018-38. doi: 10.1039/d4md00343h. Online ahead of print. RSC Med Chem. 2024. PMID: 39345716 Free PMC article.
Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model.
Seborova K, Koucka K, Spalenkova A, Holy P, Ehrlichova M, Sychra T, Chen L, Bendale H, Ojima I, Sandoval-Acuña C, Truksa J, Soucek P, Vaclavikova R. Seborova K, et al. Among authors: koucka k. Front Pharmacol. 2022 Nov 9;13:971905. doi: 10.3389/fphar.2022.971905. eCollection 2022. Front Pharmacol. 2022. PMID: 36438837 Free PMC article.
The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes.
Seborova K, Kloudova-Spalenkova A, Koucka K, Holy P, Ehrlichova M, Wang C, Ojima I, Voleska I, Daniel P, Balusikova K, Jelinek M, Kovar J, Rob L, Hruda M, Mrhalova M, Soucek P, Vaclavikova R. Seborova K, et al. Among authors: koucka k. Int J Mol Sci. 2021 Dec 22;23(1):73. doi: 10.3390/ijms23010073. Int J Mol Sci. 2021. PMID: 35008510 Free PMC article.