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SARS-CoV-2 infection is associated with intestinal permeability, systemic inflammation, and microbial dysbiosis in hospitalized patients.
Basting CM, Langat R, Broedlow CA, Guerrero CR, Bold TD, Bailey M, Velez A, Schroeder T, Short-Miller J, Cromarty R, Mayer ZJ, Southern PJ, Schacker TW, Safo SE, Bramante CT, Tignanelli CJ, Schifanella L, Klatt NR. Basting CM, et al. Among authors: bramante ct. Microbiol Spectr. 2024 Nov 5;12(11):e0068024. doi: 10.1128/spectrum.00680-24. Epub 2024 Sep 30. Microbiol Spectr. 2024. PMID: 39345212 Free PMC article.
Observational Study of Metformin and Risk of Mortality in Patients Hospitalized with Covid-19.
Bramante CT, Ingraham NE, Murray TA, Marmor S, Hovertsen S, Gronski J, McNeil C, Feng R, Guzman G, Abdelwahab N, King S, Meehan T, Pendleton KM, Benson B, Vojta D, Tignanelli CJ. Bramante CT, et al. medRxiv [Preprint]. 2020 Jun 28:2020.06.19.20135095. doi: 10.1101/2020.06.19.20135095. medRxiv. 2020. Update in: Lancet Healthy Longev. 2021 Jan;2(1):e34-e41. doi: 10.1016/S2666-7568(20)30033-7 PMID: 32607520 Free PMC article. Updated. Preprint.
mTOR inhibition in COVID-19: A commentary and review of efficacy in RNA viruses.
Karam BS, Morris RS, Bramante CT, Puskarich M, Zolfaghari EJ, Lotfi-Emran S, Ingraham NE, Charles A, Odde DJ, Tignanelli CJ. Karam BS, et al. Among authors: bramante ct. J Med Virol. 2021 Apr;93(4):1843-1846. doi: 10.1002/jmv.26728. Epub 2020 Dec 17. J Med Virol. 2021. PMID: 33314219 Free PMC article. Review.
Metformin and risk of mortality in patients hospitalised with COVID-19: a retrospective cohort analysis.
Bramante CT, Ingraham NE, Murray TA, Marmor S, Hovertsen S, Gronski J, McNeil C, Feng R, Guzman G, Abdelwahab N, King S, Tamariz L, Meehan T, Pendleton KM, Benson B, Vojta D, Tignanelli CJ. Bramante CT, et al. Lancet Healthy Longev. 2021 Jan;2(1):e34-e41. doi: 10.1016/S2666-7568(20)30033-7. Epub 2020 Dec 3. Lancet Healthy Longev. 2021. PMID: 33521772 Free PMC article.
Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity.
Bramante CT, Buse J, Tamaritz L, Palacio A, Cohen K, Vojta D, Liebovitz D, Mitchell N, Nicklas J, Lingvay I, Clark JM, Aronne LJ, Anderson E, Usher M, Demmer R, Melton GB, Ingraham N, Tignanelli CJ. Bramante CT, et al. J Med Virol. 2021 Jul;93(7):4273-4279. doi: 10.1002/jmv.26873. Epub 2021 Mar 23. J Med Virol. 2021. PMID: 33580540 Free PMC article.
Vaccination Against SARS-CoV-2 Is Associated With a Lower Viral Load and Likelihood of Systemic Symptoms.
Bramante CT, Proper JL, Boulware DR, Karger AB, Murray T, Rao V, Hagen A, Tignanelli CJ, Puskarich M, Cohen K, Liebovitz DM, Klatt NR, Broedlow C, Hartman KM, Nicklas J, Ibrahim S, Zaman A, Saveraid H, Belani H, Ingraham N, Christensen G, Siegel L, Sherwood NE, Fricton R, Lee S, Odde DJ, Buse JB, Huling JD. Bramante CT, et al. Open Forum Infect Dis. 2022 Feb 20;9(5):ofac066. doi: 10.1093/ofid/ofac066. eCollection 2022 May. Open Forum Infect Dis. 2022. PMID: 35392460 Free PMC article.
Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19.
Bramante CT, Huling JD, Tignanelli CJ, Buse JB, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Proper JL, Siegel LK, Klatt NR, Odde DJ, Luke DG, Anderson B, Karger AB, Ingraham NE, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid HG, Tordsen WJ, Pullen MF, Biros M, Sherwood NE, Thompson JL, Boulware DR, Murray TA; COVID-OUT Trial Team. Bramante CT, et al. N Engl J Med. 2022 Aug 18;387(7):599-610. doi: 10.1056/NEJMoa2201662. N Engl J Med. 2022. PMID: 36070710 Free PMC article. Clinical Trial.
Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Booster on Coronavirus Disease 2019 (COVID-19) Symptom Severity Over Time in the COVID-OUT Trial.
Boulware DR, Murray TA, Proper JL, Tignanelli CJ, Buse JB, Liebovitz DM, Nicklas JM, Cohen K, Puskarich MA, Belani HK, Siegel LK, Klatt NR, Odde DJ, Karger AB, Ingraham NE, Hartman KM, Rao V, Hagen AA, Patel B, Fenno SL, Avula N, Reddy NV, Erickson SM, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid HG, Tordsen WJ, Pullen MF, Sherwood NE, Huling JD, Bramante CT; COVID-OUT study team. Boulware DR, et al. Among authors: bramante ct. Clin Infect Dis. 2023 Feb 8;76(3):e1-e9. doi: 10.1093/cid/ciac772. Clin Infect Dis. 2023. PMID: 36124697 Free PMC article. Clinical Trial.
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial.
Bramante CT, Buse JB, Liebovitz DM, Nicklas JM, Puskarich MA, Cohen K, Belani HK, Anderson BJ, Huling JD, Tignanelli CJ, Thompson JL, Pullen M, Wirtz EL, Siegel LK, Proper JL, Odde DJ, Klatt NR, Sherwood NE, Lindberg SM, Karger AB, Beckman KB, Erickson SM, Fenno SL, Hartman KM, Rose MR, Mehta T, Patel B, Griffiths G, Bhat NS, Murray TA, Boulware DR; COVID-OUT Study Team. Bramante CT, et al. Lancet Infect Dis. 2023 Oct;23(10):1119-1129. doi: 10.1016/S1473-3099(23)00299-2. Epub 2023 Jun 8. Lancet Infect Dis. 2023. PMID: 37302406 Free PMC article. Clinical Trial.
81 results