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Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.
Heflich RH, Bishop ME, Mittelstaedt RA, Yan J, Guerrero SK, Sims AM, Mitchell K, Moore N, Li X, Mei N, Elespuru RK, King ST, Keire DA, Kruhlak NL, Dorsam RT, Raw AS, Davis Bruno KL, McGovern TJ, Atrakchi AH. Heflich RH, et al. Among authors: keire da. Regul Toxicol Pharmacol. 2024 Nov;153:105709. doi: 10.1016/j.yrtph.2024.105709. Epub 2024 Sep 28. Regul Toxicol Pharmacol. 2024. PMID: 39343352
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays.
Li X, Le Y, Seo JE, Guo X, Li Y, Chen S, Mittelstaedt RA, Moore N, Guerrero S, Sims A, King ST, Atrakchi AH, McGovern TJ, Davis-Bruno KL, Keire DA, Elespuru RK, Heflich RH, Mei N. Li X, et al. Among authors: keire da. Regul Toxicol Pharmacol. 2023 Jun;141:105410. doi: 10.1016/j.yrtph.2023.105410. Epub 2023 May 18. Regul Toxicol Pharmacol. 2023. PMID: 37210026 Free PMC article.
Bumetanide as a Model NDSRI Substrate: N-nitrosobumetanide Impurity Formation and its Inhibition in Bumetanide Tablets.
Shakleya D, Asmelash B, Alayoubi A, Abrigo N, Mohammad A, Wang J, Zhang J, Yang J, Marzan TA, Li D, Shaklah M, Alsharif FM, Desai S, Faustino PJ, Ashraf M, O'Connor T, Vera M, Raw A, Sayeed VA, Keire D. Shakleya D, et al. J Pharm Sci. 2023 Dec;112(12):3075-3087. doi: 10.1016/j.xphs.2023.06.013. Epub 2023 Jun 24. J Pharm Sci. 2023. PMID: 37364772
Performance Characteristics of Mass Spectrometry-Based Analytical Procedures for Quantitation of Nitrosamines in Pharmaceuticals: Insights from an Inter-laboratory Study.
Yang J, Kakarla R, Marzan T, Sherwin B, George M, Bennett J, Basutto J, Su Y, Ollerenshaw J, Morin J, Rebière H, Maggio AF, Kermaïdic A, Gervela E, Brenier C, Civade C, Chauvey D, Duperray F, Wollein U, Conti M, Tromp J, Meyer S, Wanko R, Wierer M, Bertrand M, Rodriguez J, Sommers C, Keire D. Yang J, et al. J Pharm Sci. 2023 Oct;112(10):2685-2695. doi: 10.1016/j.xphs.2023.07.022. Epub 2023 Jul 29. J Pharm Sci. 2023. PMID: 37524228 Free article.
98 results