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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.
Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas AS, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M. Wani AH, et al. BMC Med Genomics. 2024 Sep 27;17(1):235. doi: 10.1186/s12920-024-02002-6. BMC Med Genomics. 2024. PMID: 39334086 Free PMC article.
Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity.
Katrinli S, Stevens J, Wani AH, Lori A, Kilaru V, van Rooij SJH, Hinrichs R, Powers A, Gillespie CF, Michopoulos V, Gautam A, Jett M, Hammamieh R, Yang R, Wildman D, Qu A, Koenen K, Aiello AE, Jovanovic T, Uddin M, Ressler KJ, Smith AK. Katrinli S, et al. Among authors: wani ah. Neuropsychopharmacology. 2020 Sep;45(10):1609-1616. doi: 10.1038/s41386-020-0700-5. Epub 2020 May 7. Neuropsychopharmacology. 2020. PMID: 32380512 Free PMC article.
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.
Smith AK, Ratanatharathorn A, Maihofer AX, Naviaux RK, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Boks MP, Bromet E, Dennis M, Galea S, Garrett ME, Geuze E, Guffanti G, Hauser MA, Katrinli S, Kilaru V, Kessler RC, Kimbrel NA, Koenen KC, Kuan PF, Li K, Logue MW, Lori A, Luft BJ, Miller MW, Naviaux JC, Nugent NR, Qin X, Ressler KJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Wang L, Youssef NA; INTRuST Clinical Consortium; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup; Uddin M, Nievergelt CM. Smith AK, et al. Nat Commun. 2020 Nov 24;11(1):5965. doi: 10.1038/s41467-020-19615-x. Nat Commun. 2020. PMID: 33235198 Free PMC article.
RANDOMIZE: A Web Server for Data Randomization.
Wani AH, Armstrong D, Dahrendorff J, Uddin M. Wani AH, et al. Arch Proteom Bioinform. 2020;1(1):31-37. Arch Proteom Bioinform. 2020. PMID: 33554223 Free PMC article.
Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress.
Katrinli S, Maihofer AX, Wani AH, Pfeiffer JR, Ketema E, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Kessler RC, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Logue MW, Nievergelt CM, Smith AK, Uddin M. Katrinli S, et al. Among authors: wani ah. Mol Psychiatry. 2022 Mar;27(3):1720-1728. doi: 10.1038/s41380-021-01398-2. Epub 2022 Jan 7. Mol Psychiatry. 2022. PMID: 34992238 Free PMC article.
DNA methylation of Nuclear Factor of Activated T Cells 1 mediates the prospective relation between exposure to different traumatic event types and post-traumatic stress disorder.
Occean JR, Wani AH, Donglasan J, Aiello AE, Galea S, Koenen KC, Qu A, Wildman DE, Uddin M. Occean JR, et al. Among authors: wani ah. Psychiatry Res. 2022 May;311:114510. doi: 10.1016/j.psychres.2022.114510. Epub 2022 Mar 19. Psychiatry Res. 2022. PMID: 35349860 Free PMC article.
Community engagement in epigenomic and neurocognitive research on post-traumatic stress disorder in Rwandans exposed to the 1994 genocide against the Tutsi: lessons learned.
Musanabaganwa C, Jansen S, Wani A, Rugamba A, Mutabaruka J, Rutembesa E, Uwineza A, Fatumo S, Hermans EJ, Souopgui J, Wildman DE, Uddin M, Roozendaal B, Njemini R, Mutesa L. Musanabaganwa C, et al. Epigenomics. 2022 Aug;14(15):887-895. doi: 10.2217/epi-2022-0079. Epub 2022 Aug 25. Epigenomics. 2022. PMID: 36004496 Free PMC article. Review.
98 results