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Page 1
SURF2 is a MDM2 antagonist in triggering the nucleolar stress response.
Tagnères S, Santo PE, Radermecker J, Rinaldi D, Froment C, Provost Q, Bongers M, Capeille S, Watkins N, Marcoux J, Gleizes PE, Marcel V, Plisson-Chastang C, Lebaron S. Tagnères S, et al. Among authors: santo pe. Nat Commun. 2024 Sep 27;15(1):8404. doi: 10.1038/s41467-024-52659-x. Nat Commun. 2024. PMID: 39333141 Free PMC article.
CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function.
Pires C, Marques IJ, Valério M, Saramago A, Santo PE, Santos S, Silva M, Moura MM, Matos J, Pereira T, Cabrera R, Lousa D, Leite V, Bandeiras TM, Vicente JB, Cavaco BM. Pires C, et al. Among authors: santo pe. J Biol Chem. 2024 Mar;300(3):105767. doi: 10.1016/j.jbc.2024.105767. Epub 2024 Feb 16. J Biol Chem. 2024. PMID: 38367672 Free PMC article.
Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases.
Dos Santos Morais R, Santo PE, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva ACF, Hessmann S, Morellet N, M F Sousa P, Vandermoere F, Bertrand E, Charpentier B, Bandeiras TM, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X. Dos Santos Morais R, et al. Among authors: santo pe. J Mol Biol. 2022 Oct 15;434(19):167760. doi: 10.1016/j.jmb.2022.167760. Epub 2022 Jul 25. J Mol Biol. 2022. PMID: 35901867 Free article.
The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.
Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo PE, Bourguet M, C F Paiva A, Bragantini B, Chagot ME, Robert MC, Abeza C, Fabre P, Fort P, Vandermoere F, M F Sousa P, Rain JC, Charpentier B, Cianférani S, Bandeiras TM, Pradet-Balade B, Manival X, Bertrand E. Maurizy C, et al. Among authors: santo pe. Nat Commun. 2018 May 29;9(1):2093. doi: 10.1038/s41467-018-04431-1. Nat Commun. 2018. PMID: 29844425 Free PMC article.
A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?
Vicente JB, Colaço HG, Malagrinò F, Santo PE, Gutierres A, Bandeiras TM, Leandro P, Brito JA, Giuffrè A. Vicente JB, et al. Among authors: santo pe. Oxid Med Cell Longev. 2017;2017:8940321. doi: 10.1155/2017/8940321. Epub 2017 Mar 22. Oxid Med Cell Longev. 2017. PMID: 28421128 Free PMC article.