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AANAT kinetics of CoASH-targeted electrophiles of tryptamine and related analogs.
Wandrey N, Hamilton L, Boley J, Haynes A, Redinger M, Hill M, Hagemeister M, Cole PA, Moxley MA, Thomas AA. Wandrey N, et al. Among authors: cole pa. Bioorg Med Chem Lett. 2024 Nov 15;113:129975. doi: 10.1016/j.bmcl.2024.129975. Epub 2024 Sep 25. Bioorg Med Chem Lett. 2024. PMID: 39332648
Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity.
Abeywardana MY, Whedon SD, Lee K, Nam E, Dovarganes R, DuBois-Coyne S, Haque IA, Wang ZA, Cole PA. Abeywardana MY, et al. Among authors: cole pa. J Biol Chem. 2024 Sep;300(9):107722. doi: 10.1016/j.jbc.2024.107722. Epub 2024 Aug 28. J Biol Chem. 2024. PMID: 39214297 Free PMC article.
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.
Waterbury AL, Kwok HS, Lee C, Narducci DN, Freedy AM, Su C, Raval S, Reiter AH, Hawkins W, Lee K, Li J, Hoenig SM, Vinyard ME, Cole PA, Hansen AS, Carr SA, Papanastasiou M, Liau BB. Waterbury AL, et al. Among authors: cole pa. Mol Cell. 2024 Jun 20;84(12):2238-2254.e11. doi: 10.1016/j.molcel.2024.05.017. Epub 2024 Jun 12. Mol Cell. 2024. PMID: 38870936
Structural requirements for activity of Mind bomb1 in Notch signaling.
Cao R, Gozlan O, Airich A, Tveriakhina L, Zhou H, Jiang H, Cole PA, Aster JC, Klein T, Sprinzak D, Blacklow SC. Cao R, et al. Among authors: cole pa. Structure. 2024 Oct 3;32(10):1667-1676.e5. doi: 10.1016/j.str.2024.07.011. Epub 2024 Aug 8. Structure. 2024. PMID: 39121852
Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics.
Akinci E, Cha M, Lin L, Yeo G, Hamilton MC, Donahue CJ, Bermudez-Cabrera HC, Zanetti LC, Chen M, Barkal SA, Khowpinitchai B, Chu N, Velimirovic M, Jodhani R, Fife JD, Sovrovic M, Cole PA, Davey RA, Cassa CA, Sherwood RI. Akinci E, et al. Among authors: cole pa. bioRxiv [Preprint]. 2020 Aug 28:2020.08.27.270819. doi: 10.1101/2020.08.27.270819. bioRxiv. 2020. PMID: 32869031 Free PMC article. Preprint.
493 results