Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

13 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Evaluation of the in vivo acute toxicity and in vitro genotoxicity and mutagenicity of synthetic β-carboline alkaloids with selective cytotoxic activity against ovarian and breast cancer cell lines.
Tecchio KB, Alves FM, Alves JD, Barbosa CS, Salgado MAR, Santos VJDSVD, Varotti FP, Campos-Junior PHA, Viana GHR, Santos FVD. Tecchio KB, et al. Among authors: viana ghr. Mutat Res Genet Toxicol Environ Mutagen. 2024 Oct;899:503808. doi: 10.1016/j.mrgentox.2024.503808. Epub 2024 Aug 10. Mutat Res Genet Toxicol Environ Mutagen. 2024. PMID: 39326936
Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines.
Oliveira JT, Franco FN, Tecchio KB, Gonçalves AMMN, Barbosa CS, Ribeiro RIMA, Viana GHR, Santos VJDSVD, Santos FVD. Oliveira JT, et al. Among authors: viana ghr. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503294. doi: 10.1016/j.mrgentox.2020.503294. Epub 2020 Nov 7. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 33551097 Free article.
Nanoemulsion composed of 10-(4,5-dihydrothiazol-2-yl)thio)decan-1-ol), a synthetic analog of 3-alkylpiridine marine alkaloid: development, characterization, and antimalarial activity.
Silva MGD, Cardoso JF, Perasoli FB, Branquinho RT, Mourão RS, Tavares HDS, Xocaira MLCT, Guimarães DSM, Viana GHR, Varotti FP, Silva GRD. Silva MGD, et al. Among authors: viana ghr. Eur J Pharm Sci. 2020 Aug 1;151:105382. doi: 10.1016/j.ejps.2020.105382. Epub 2020 May 26. Eur J Pharm Sci. 2020. PMID: 32470575
Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability.
Guimarães DSM, de Sousa Luz LS, do Nascimento SB, Silva LR, de Miranda Martins NR, de Almeida HG, de Souza Reis V, Maluf SEC, Budu A, Marinho JA, Abramo C, Carmona AK, da Silva MG, da Silva GR, Kemmer VM, Butera AP, Ribeiro-Viana RM, Gazarini ML, Júnior CSN, Guimarães L, Dos Santos FV, de Castro WV, Viana GHR, de Brito CFA, de Pilla Varotti F. Guimarães DSM, et al. Among authors: viana ghr. Eur J Pharm Sci. 2019 Oct 1;138:105015. doi: 10.1016/j.ejps.2019.105015. Epub 2019 Jul 22. Eur J Pharm Sci. 2019. PMID: 31344442
New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
Soares RR, da Silva JM, Carlos BC, da Fonseca CC, de Souza LS, Lopes FV, de Paula Dias RM, Moreira PO, Abramo C, Viana GH, de Pila Varotti F, da Silva AD, Scopel KK. Soares RR, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2308-13. doi: 10.1016/j.bmcl.2015.04.014. Epub 2015 Apr 11. Bioorg Med Chem Lett. 2015. PMID: 25920564
Antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate.
de Oliveira ME, Cenzi G, Nunes RR, Andrighetti CR, de Sousa Valadão DM, Dos Reis C, Simões CM, Nunes RJ, Júnior MC, Taranto AG, Sanchez BA, Viana GH, de Pilla Varotti F. de Oliveira ME, et al. Molecules. 2013 Dec 10;18(12):15276-87. doi: 10.3390/molecules181215276. Molecules. 2013. PMID: 24335577 Free PMC article.
A 3-alkylpyridine-bearing alkaloid exhibits potent antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with no detectable resistance.
Herrera KMS, Lopes GFM, Oliveira ME, Sousa JF, Lima WG, Silva FK, Brito JCM, Gomes AJPS, Viana GHR, Soares AC, Ferreira JMS. Herrera KMS, et al. Among authors: viana ghr. Microbiol Res. 2022 Aug;261:127073. doi: 10.1016/j.micres.2022.127073. Epub 2022 May 16. Microbiol Res. 2022. PMID: 35636092 Free article.
13 results