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Evaluation of the in vivo acute toxicity and in vitro genotoxicity and mutagenicity of synthetic β-carboline alkaloids with selective cytotoxic activity against ovarian and breast cancer cell lines.
Tecchio KB, Alves FM, Alves JD, Barbosa CS, Salgado MAR, Santos VJDSVD, Varotti FP, Campos-Junior PHA, Viana GHR, Santos FVD. Tecchio KB, et al. Mutat Res Genet Toxicol Environ Mutagen. 2024 Oct;899:503808. doi: 10.1016/j.mrgentox.2024.503808. Epub 2024 Aug 10. Mutat Res Genet Toxicol Environ Mutagen. 2024. PMID: 39326936
Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines.
Oliveira JT, Franco FN, Tecchio KB, Gonçalves AMMN, Barbosa CS, Ribeiro RIMA, Viana GHR, Santos VJDSVD, Santos FVD. Oliveira JT, et al. Among authors: tecchio kb. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503294. doi: 10.1016/j.mrgentox.2020.503294. Epub 2020 Nov 7. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 33551097 Free article.