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Page 1
Designed endocytosis-inducing proteins degrade targets and amplify signals.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Tang C, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yi L, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Duran Gonzalez MJ, Bennett NR, Venkatesh P, Ahlrichs M, Dobbins C, Yang W, Wang X, Sahtoe DD, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Roybal KT, Greisen PJ, Li X, Bernardes GJL, Bertozzi CR, Baker D. Huang B, et al. Among authors: shivaei s. Nature. 2024 Sep 25. doi: 10.1038/s41586-024-07948-2. Online ahead of print. Nature. 2024. PMID: 39322662
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Gonzalez MJD, Bennett NR, Venkatesh P, Satoe D, Ahlrichs M, Dobbins C, Yang W, Wang X, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Bernardes GJL, Roybal KT, Greisen P Jr, Li X, Bertozzi C, Baker D. Huang B, et al. Among authors: shivaei s. bioRxiv [Preprint]. 2023 Sep 20:2023.08.19.553321. doi: 10.1101/2023.08.19.553321. bioRxiv. 2023. PMID: 37781607 Free PMC article. Preprint.
Biomolecular actuators for genetically selective acoustic manipulation of cells.
Wu D, Baresch D, Cook C, Ma Z, Duan M, Malounda D, Maresca D, Abundo MP, Lee J, Shivaei S, Mittelstein DR, Qiu T, Fischer P, Shapiro MG. Wu D, et al. Among authors: shivaei s. Sci Adv. 2023 Feb 22;9(8):eadd9186. doi: 10.1126/sciadv.add9186. Epub 2023 Feb 22. Sci Adv. 2023. PMID: 36812320 Free PMC article.
Acoustically triggered mechanotherapy using genetically encoded gas vesicles.
Bar-Zion A, Nourmahnad A, Mittelstein DR, Shivaei S, Yoo S, Buss MT, Hurt RC, Malounda D, Abedi MH, Lee-Gosselin A, Swift MB, Maresca D, Shapiro MG. Bar-Zion A, et al. Among authors: shivaei s. Nat Nanotechnol. 2021 Dec;16(12):1403-1412. doi: 10.1038/s41565-021-00971-8. Epub 2021 Sep 27. Nat Nanotechnol. 2021. PMID: 34580468
Ultrasensitive ultrasound imaging of gene expression with signal unmixing.
Sawyer DP, Bar-Zion A, Farhadi A, Shivaei S, Ling B, Lee-Gosselin A, Shapiro MG. Sawyer DP, et al. Among authors: shivaei s. Nat Methods. 2021 Aug;18(8):945-952. doi: 10.1038/s41592-021-01229-w. Epub 2021 Aug 5. Nat Methods. 2021. PMID: 34354290 Free PMC article.