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Page 1
Engineered receptors for soluble cellular communication and disease sensing.
Piraner DI, Abedi MH, Duran Gonzalez MJ, Chazin-Gray A, Lin A, Zhu I, Ravindran PT, Schlichthaerle T, Huang B, Bearchild TH, Lee D, Wyman S, Jun YW, Baker D, Roybal KT. Piraner DI, et al. Nature. 2024 Nov 14. doi: 10.1038/s41586-024-08366-0. Online ahead of print. Nature. 2024. PMID: 39542025
Designed endocytosis-inducing proteins degrade targets and amplify signals.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Tang C, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yi L, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Duran Gonzalez MJ, Bennett NR, Venkatesh P, Ahlrichs M, Dobbins C, Yang W, Wang X, Sahtoe DD, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Roybal KT, Greisen PJ, Li X, Bernardes GJL, Bertozzi CR, Baker D. Huang B, et al. Among authors: piraner di. Nature. 2024 Sep 25. doi: 10.1038/s41586-024-07948-2. Online ahead of print. Nature. 2024. PMID: 39322662
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Gonzalez MJD, Bennett NR, Venkatesh P, Satoe D, Ahlrichs M, Dobbins C, Yang W, Wang X, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Bernardes GJL, Roybal KT, Greisen P Jr, Li X, Bertozzi C, Baker D. Huang B, et al. Among authors: piraner di. bioRxiv [Preprint]. 2023 Sep 20:2023.08.19.553321. doi: 10.1101/2023.08.19.553321. bioRxiv. 2023. PMID: 37781607 Free PMC article. Preprint.
Thermal Control of Engineered T-cells.
Abedi MH, Lee J, Piraner DI, Shapiro MG. Abedi MH, et al. Among authors: piraner di. ACS Synth Biol. 2020 Aug 21;9(8):1941-1950. doi: 10.1021/acssynbio.0c00238. Epub 2020 Aug 4. ACS Synth Biol. 2020. PMID: 32786924
Modular Thermal Control of Protein Dimerization.
Piraner DI, Wu Y, Shapiro MG. Piraner DI, et al. ACS Synth Biol. 2019 Oct 18;8(10):2256-2262. doi: 10.1021/acssynbio.9b00275. Epub 2019 Sep 12. ACS Synth Biol. 2019. PMID: 31491082