Harris LD - Search Results

1

An efficient regioconvergent synthesis of 3-aza-obeticholic acid.

Harris LD, Aponte RAL, Jiao W, Cameron SA, Weymouth-Wilson A, Furneaux RH, Compton BJ, Luxenburger A. Harris LD, et al. Steroids. 2024 Dec;212:109517. doi: 10.1016/j.steroids.2024.109517. Epub 2024 Sep 24. Steroids. 2024. PMID: 39322098 Free article.

2

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction.

Harris L, Mee SP, Furneaux RH, Gainsford GJ, Luxenburger A. Harris L, et al. J Org Chem. 2011 Jan 21;76(2):358-72. doi: 10.1021/jo1018816. Epub 2010 Dec 29. J Org Chem. 2011. PMID: 21190319

3

The post-lockdown period should be used to acquire effective therapies for future resurgence in SARS-Cov-2 infections.

Krause KL, Furneaux R, Benjes P, Brimble M, Davidson T, Denny W, Harris L, Hinkley S, Tyler P, Ussher JE, Ward V. Krause KL, et al. N Z Med J. 2020 Apr 24;133(1513):107-111. N Z Med J. 2020. PMID: 32325475

4

Chemical Synthesis of the Antiviral Nucleotide Analogue ddhCTP.

Wood JM, Evans GB, Grove TL, Almo SC, Cameron SA, Furneaux RH, Harris LD. Wood JM, et al. Among authors: harris ld. J Org Chem. 2021 Jul 2;86(13):8843-8850. doi: 10.1021/acs.joc.1c00761. Epub 2021 Jun 14. J Org Chem. 2021. PMID: 34126010

5

Synthesis of 12β-Methyl-18-nor-bile Acids.

Luxenburger A, Harris LD, Ure EM, Landaeta Aponte RA, Woolhouse AD, Cameron SA, Ling CD, Piltz RO, Lewis AR, Gainsford GJ, Weymouth-Wilson A, Furneaux RH. Luxenburger A, et al. Among authors: harris ld. ACS Omega. 2021 Sep 14;6(38):25019-25039. doi: 10.1021/acsomega.1c04199. eCollection 2021 Sep 28. ACS Omega. 2021. PMID: 34604682 Free PMC article.

6

Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid.

Mellott DM, Torres D, Krieger IV, Cameron SA, Moghadamchargari Z, Laganowsky A, Sacchettini JC, Meek TD, Harris LD. Mellott DM, et al. Among authors: harris ld. J Am Chem Soc. 2021 Oct 27;143(42):17666-17676. doi: 10.1021/jacs.1c07970. Epub 2021 Oct 19. J Am Chem Soc. 2021. PMID: 34664502

7

Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.

Luxenburger A, Bougen-Zhukov N, Fraser MG, Beetham H, Harris LD, Schmidt D, Cameron SA, Guilford PJ, Evans GB. Luxenburger A, et al. Among authors: harris ld. J Med Chem. 2021 Dec 23;64(24):18114-18142. doi: 10.1021/acs.jmedchem.1c01609. Epub 2021 Dec 8. J Med Chem. 2021. PMID: 34878770

8

Synthesis of 12β-methyl-18-nor-avicholic acid analogues as potential TGR5 agonists.

Ure EM, Harris LD, Cameron SA, Weymouth-Wilson A, Furneaux RH, Pitman JL, Hinkley SF, Luxenburger A. Ure EM, et al. Among authors: harris ld. Org Biomol Chem. 2022 May 4;20(17):3511-3527. doi: 10.1039/d1ob02401a. Org Biomol Chem. 2022. PMID: 35230376

9

Synthesis of Novel C/D Ring Modified Bile Acids.

Landaeta Aponte RA, Luxenburger A, Cameron SA, Weymouth-Wilson A, Furneaux RH, Harris LD, Compton BJ. Landaeta Aponte RA, et al. Among authors: harris ld. Molecules. 2022 Apr 6;27(7):2364. doi: 10.3390/molecules27072364. Molecules. 2022. PMID: 35408759 Free PMC article.

10

3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson's Disease.

Luxenburger A, Clemmens H, Hastings C, Harris LD, Ure EM, Cameron SA, Aasly J, Bandmann O, Weymouth-Wilson A, Furneaux RH, Mortiboys H. Luxenburger A, et al. Among authors: harris ld. Biomolecules. 2022 Dec 30;13(1):76. doi: 10.3390/biom13010076. Biomolecules. 2022. PMID: 36671460 Free PMC article.

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