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Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling.
Deroche L, Aranzana-Climent V, Rozenholc A, Prouvensier L, Darnaud L, Grégoire N, Marchand S, Ploy M-C, François B, Couet W, Barraud O, Buyck JM. Deroche L, et al. Among authors: couet w. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0048023. doi: 10.1128/aac.00480-23. Epub 2023 Sep 11. Antimicrob Agents Chemother. 2023. PMID: 37695298 Free PMC article.
Population pharmacokinetic/pharmacodynamic study suggests continuous infusion of ceftaroline daily dose in ventilated critical care patients with early-onset pneumonia and augmented renal clearance.
Chauzy A, Gregoire N, Ferrandière M, Lasocki S, Ashenoune K, Seguin P, Boisson M, Couet W, Marchand S, Mimoz O, Dahyot-Fizelier C. Chauzy A, et al. Among authors: couet w. J Antimicrob Chemother. 2022 Oct 28;77(11):3173-3179. doi: 10.1093/jac/dkac299. J Antimicrob Chemother. 2022. PMID: 36059138 Free PMC article.
Activation of class 1 integron integrase is promoted in the intestinal environment.
Baltazar M, Bourgeois-Nicolaos N, Larroudé M, Couet W, Uwajeneza S, Doucet-Populaire F, Ploy MC, Da Re S. Baltazar M, et al. Among authors: couet w. PLoS Genet. 2022 Apr 28;18(4):e1010177. doi: 10.1371/journal.pgen.1010177. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35482826 Free PMC article.
185 results