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23 results

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Page 1
Selective Enhancer Gain-of-Function Deregulates MYC Expression in Multiple Myeloma.
Rahmat M, Clement K, Alberge JB, Sklavenitis-Pistofidis R, Kodgule R, Fulco CP, Heilpern-Mallory D, Nilsson K, Dorfman D, Engreitz JM, Getz G, Pinello L, Ryan RJH, Ghobrial IM. Rahmat M, et al. Among authors: fulco cp. Cancer Res. 2024 Dec 16;84(24):4173-4183. doi: 10.1158/0008-5472.CAN-24-1440. Cancer Res. 2024. PMID: 39312195
Selective Enhancer Dependencies in MYC -Intact and MYC -Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.
Iyer AR, Gurumurthy A, Kodgule R, Aguilar AR, Saari T, Ramzan A, Rausch D, Gupta J, Hall CN, Runge JS, Weiss M, Rahmat M, Anyoha R, Fulco CP, Ghobrial IM, Engreitz J, Cieslik MP, Ryan RJH. Iyer AR, et al. Among authors: fulco cp. bioRxiv [Preprint]. 2023 May 3:2023.05.02.538892. doi: 10.1101/2023.05.02.538892. bioRxiv. 2023. PMID: 37205448 Free PMC article. Preprint.
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Munschauer M, Nguyen CT, Sirokman K, Hartigan CR, Hogstrom L, Engreitz JM, Ulirsch JC, Fulco CP, Subramanian V, Chen J, Schenone M, Guttman M, Carr SA, Lander ES. Munschauer M, et al. Among authors: fulco cp. Nature. 2018 Sep;561(7721):132-136. doi: 10.1038/s41586-018-0453-z. Epub 2018 Aug 27. Nature. 2018. PMID: 30150775
Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.
Fulco CP, Nasser J, Jones TR, Munson G, Bergman DT, Subramanian V, Grossman SR, Anyoha R, Doughty BR, Patwardhan TA, Nguyen TH, Kane M, Perez EM, Durand NC, Lareau CA, Stamenova EK, Aiden EL, Lander ES, Engreitz JM. Fulco CP, et al. Nat Genet. 2019 Dec;51(12):1664-1669. doi: 10.1038/s41588-019-0538-0. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784727 Free PMC article.
Compatibility rules of human enhancer and promoter sequences.
Bergman DT, Jones TR, Liu V, Ray J, Jagoda E, Siraj L, Kang HY, Nasser J, Kane M, Rios A, Nguyen TH, Grossman SR, Fulco CP, Lander ES, Engreitz JM. Bergman DT, et al. Among authors: fulco cp. Nature. 2022 Jul;607(7917):176-184. doi: 10.1038/s41586-022-04877-w. Epub 2022 May 20. Nature. 2022. PMID: 35594906 Free PMC article.
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Joung J, et al. Among authors: fulco cp. Nature. 2017 Aug 17;548(7667):343-346. doi: 10.1038/nature23451. Epub 2017 Aug 11. Nature. 2017. PMID: 28792927 Free PMC article.
Rewriting regulatory DNA to dissect and reprogram gene expression.
Martyn GE, Montgomery MT, Jones H, Guo K, Doughty BR, Linder J, Chen Z, Cochran K, Lawrence KA, Munson G, Pampari A, Fulco CP, Kelley DR, Lander ES, Kundaje A, Engreitz JM. Martyn GE, et al. Among authors: fulco cp. bioRxiv [Preprint]. 2023 Dec 21:2023.12.20.572268. doi: 10.1101/2023.12.20.572268. bioRxiv. 2023. PMID: 38187584 Free PMC article. Preprint.
23 results