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Page 1
Allosteric antagonism of insect odorant receptor ion channels.
Jones PL, Pask GM, Romaine IM, Taylor RW, Reid PR, Waterson AG, Sulikowski GA, Zwiebel LJ. Jones PL, et al. Among authors: romaine im. PLoS One. 2012;7(1):e30304. doi: 10.1371/journal.pone.0030304. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272331 Free PMC article.
Narrow SAR in odorant sensing Orco receptor agonists.
Romaine IM, Taylor RW, Saidu SP, Kim K, Sulikowski GA, Zwiebel LJ, Waterson AG. Romaine IM, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2613-6. doi: 10.1016/j.bmcl.2014.04.081. Epub 2014 Apr 29. Bioorg Med Chem Lett. 2014. PMID: 24813736 Free PMC article.
VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.
McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS. McClenahan SJ, et al. Among authors: romaine im. Mol Pharmacol. 2022 May;101(5):357-370. doi: 10.1124/molpharm.121.000464. Epub 2022 Mar 3. Mol Pharmacol. 2022. PMID: 35246480 Free PMC article.
ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays antiepileptic properties in mice.
Kaufmann K, Romaine I, Days E, Pascual C, Malik A, Yang L, Zou B, Du Y, Sliwoski G, Morrison RD, Denton J, Niswender CM, Daniels JS, Sulikowski GA, Xie XS, Lindsley CW, Weaver CD. Kaufmann K, et al. ACS Chem Neurosci. 2013 Sep 18;4(9):1278-86. doi: 10.1021/cn400062a. Epub 2013 Jun 13. ACS Chem Neurosci. 2013. PMID: 23730969 Free PMC article.
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Christov PP, Kim K, Jana S, Romaine IM, Rai G, Mott BT, Allweil AA, Lamers A, Brimacombe KR, Urban DJ, Lee TD, Hu X, Lukacs CM, Davies DR, Jadhav A, Hall MD, Green N, Moore WJ, Stott GM, Flint AJ, Maloney DJ, Sulikowski GA, Waterson AG. Christov PP, et al. Among authors: romaine im. Bioorg Med Chem Lett. 2021 Jun 1;41:127974. doi: 10.1016/j.bmcl.2021.127974. Epub 2021 Mar 24. Bioorg Med Chem Lett. 2021. PMID: 33771585 Free PMC article.
16 results