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Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity.
Herrmann A, Gege C, Wangen C, Wagner S, Kögler M, Cordsmeier A, Irrgang P, Ip WH, Weil T, Hunszinger V, Groß R, Heinen N, Pfaender S, Reuter S, Klopfleisch R, Uhlig N, Eberlein V, Issmail L, Grunwald T, Hietel B, Cynis H, Münch J, Sparrer KMJ, Ensser A, Tenbusch M, Dobner T, Vitt D, Kohlhof H, Hahn F. Herrmann A, et al. Among authors: hietel b. Antiviral Res. 2024 Sep 19;231:106008. doi: 10.1016/j.antiviral.2024.106008. Online ahead of print. Antiviral Res. 2024. PMID: 39306285 Free article.
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice.
Barendrecht S, Schreurs A, Geissler S, Sabanov V, Ilse V, Rieckmann V, Eichentopf R, Künemund A, Hietel B, Wussow S, Hoffmann K, Körber-Ferl K, Pandey R, Carter GW, Demuth HU, Holzer M, Roßner S, Schilling S, Preuss C, Balschun D, Cynis H. Barendrecht S, et al. Among authors: hietel b. Alzheimers Res Ther. 2023 Jan 14;15(1):16. doi: 10.1186/s13195-022-01144-y. Alzheimers Res Ther. 2023. PMID: 36641439 Free PMC article.
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